Protein Info for CA264_14615 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: MBL fold hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: None (inferred from 60% identity to cpi:Cpin_0418)

Predicted SEED Role

"Hydroxyacylglutathione hydrolase (EC 3.1.2.6)" in subsystem Glutathione: Non-redox reactions or Methylglyoxal Metabolism (EC 3.1.2.6)

MetaCyc Pathways

methylglyoxal degradation I (2/3 steps found)
methylglyoxal degradation VIII (2/3 steps found)
superpathway of methylglyoxal degradation (4/8 steps found)

KEGG Metabolic Maps

Pyruvate metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YUK2 at UniProt or InterPro

Protein Sequence (211 amino acids)

>CA264_14615 MBL fold hydrolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MEVTCLTFNPFQENTYLLHDETNECVVVDPGCYERGEQEQLKKYIEEKGLQVVRLLNTHC
HIDHVLGNKFVADTYNVGLEIHPEDEQTLRAVPAYAPVYGFPMYAEQLPASFLREGDTVK
FGNTELQVLFTPGHAPGHVVFYNGPEKICIGGDVLFQGSIGRTDLPGGDFDTLITSIREK
MFALPDDVTVYPGHGPETTIGYEKKYNPFLR