Protein Info for CA264_14135 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: ATP-dependent chaperone ClpB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 872 TIGR03346: ATP-dependent chaperone protein ClpB" amino acids 6 to 861 (856 residues), 1303.1 bits, see alignment E=0 PF02861: Clp_N" amino acids 19 to 67 (49 residues), 18.9 bits, see alignment 8.4e-07 amino acids 97 to 143 (47 residues), 32.1 bits, see alignment 6.2e-11 PF00004: AAA" amino acids 201 to 318 (118 residues), 48 bits, see alignment E=1.1e-15 amino acids 601 to 723 (123 residues), 34 bits, see alignment E=2.2e-11 PF17871: AAA_lid_9" amino acids 342 to 442 (101 residues), 119.1 bits, see alignment E=4.7e-38 PF07724: AAA_2" amino acids 595 to 765 (171 residues), 233.6 bits, see alignment E=7.7e-73 PF00158: Sigma54_activat" amino acids 600 to 701 (102 residues), 28.6 bits, see alignment E=6.6e-10 PF07728: AAA_5" amino acids 600 to 721 (122 residues), 46.7 bits, see alignment E=2e-15 PF10431: ClpB_D2-small" amino acids 772 to 850 (79 residues), 90.5 bits, see alignment E=3.4e-29

Best Hits

Swiss-Prot: 67% identical to CLPB_BACTN: Chaperone protein ClpB (clpB) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K03695, ATP-dependent Clp protease ATP-binding subunit ClpB (inferred from 76% identity to chu:CHU_3123)

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YU87 at UniProt or InterPro

Protein Sequence (872 amino acids)

>CA264_14135 ATP-dependent chaperone ClpB (Pontibacter actiniarum KMM 6156, DSM 19842)
MNFNNYTIKAQEAIQKATEIAGGNQQQAIETGHILKAILETDENVTNFLLQKLNINGNIL
HSKLDEVVAAYPKVSGGSPYLANDAAAALQKATAYLKEFGDEYVAIEHMLLGLLAGRDKV
AGLMKDVGFNEKDLKKAIKELRGGAKVTDQNAEAKYNSLKRYAKNLNELARAGKIDPVIG
RDEEIRRVLQILSRRTKNNPVLLGEPGVGKTAIVEGLAQRMVSGDVPENLKNKTLMSLDM
GLLVAGAKYKGEFEERLKAVIKEVTDAEGEIILFIDEIHTLIGAGAGGESAMDAANLLKP
ALARGELHAIGATTLKEYQKYIEKDKALERRFQAVMVDEPSVPDAISILRGIKDKYELHH
GVRIKDDAIIASVELSNRYISDRFLPDKAIDLMDEAAAKLRIEIDSLPVELDELQRRIMQ
LEIEREAIRRENDKDKESVLSKEIADLSGKRDDLKAKWQNEKQIIEGIQKEKENIENYKL
EAEQAERSGDYGRVAELRYGKIQEAEAKLKQLQEQVREMQGENPMLKEEVNAEDIAEVVA
KWTGIPVSKMLQSDREKLLHLEQELGKRVAGQEEAIEAISDAVRRSRAGMQDPKRPIGSF
IFLGTTGVGKTELAKALADYLFNDDNAMVRIDMSEYQERHAVSRLIGAPPGYVGYDEGGQ
LTEAIRRKPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDSKGRVVNFKNTIIIMTSNIG
SHIIQSNFEKMTPLNHDEVIEQTKEEVFDLLKKSVRPEFLNRIDELVMFRPLSRGDIRKI
VNIQFRHIQQRLEEAGIQLVATDEVLDYLGEQGFDPQFGARPLKRVIQRQVLNELSKEIL
SGKINKDSVVEAVLDGGKIRFNNIDVEIPTER