Protein Info for CA264_14010 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: carbohydrate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00294: PfkB" amino acids 5 to 317 (313 residues), 101 bits, see alignment E=4.2e-33

Best Hits

KEGG orthology group: K00874, 2-dehydro-3-deoxygluconokinase [EC: 2.7.1.45] (inferred from 60% identity to phe:Phep_2264)

Predicted SEED Role

"2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)" in subsystem D-Galacturonate and D-Glucuronate Utilization or D-gluconate and ketogluconates metabolism or Entner-Doudoroff Pathway (EC 2.7.1.45)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.45

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YU65 at UniProt or InterPro

Protein Sequence (343 amino acids)

>CA264_14010 carbohydrate kinase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKNGKILTFGELLWRVASAAKGAEEPTEGLMQMHPGGAEANVAAALGRWQLPCSYFSCLP
ENELATRALTELANCGVDTSPVLRQGDRMGLYFLLTANGLSTGQVVYDRKHSAFSQLAPG
QLDWESLLQGYTWFHWSAISPALNANTAALCKEALTAARKLGLTVSVDLNHRNRLWDYGQ
SPREVMPELVALCDVVMGNIWAAHTMLGTPLAAGLGRETEQQTYLRHAAQAAADIQQQFP
QCRHVAFTFRFMDSPNHNLFYGTYHHGTRHYTSATHETQELVDRIGSGDAFMAGLIYGLY
QQLDGQAVVDFATSAAFQKLFVSGDFGKHTVTQIKAHMASAEA