Protein Info for CA264_14000 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: xylose isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 64% identical to XYLA_BACFN: Xylose isomerase (xylA) from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)

KEGG orthology group: K01805, xylose isomerase [EC: 5.3.1.5] (inferred from 83% identity to shg:Sph21_3963)

MetaCyc: 52% identical to xylose isomerase (Escherichia coli K-12 substr. MG1655)
Xylose isomerase. [EC: 5.3.1.5]

Predicted SEED Role

"Xylose isomerase (EC 5.3.1.5)" in subsystem Xylose utilization (EC 5.3.1.5)

MetaCyc Pathways

superpathway of glucose and xylose degradation (16/17 steps found)
D-xylose degradation I (2/2 steps found)
superpathway of pentose and pentitol degradation (7/42 steps found)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YUB0 at UniProt or InterPro

Protein Sequence (443 amino acids)

>CA264_14000 xylose isomerase (Pontibacter actiniarum KMM 6156, DSM 19842)
MANNTLTQTEYFKGIDKIKYEGPESDNPLAYRWYDENRMVAGKTLKDHLRFAVAYWHSFN
ADGSDPFGGPTLKFPWNEKADPIARAKDKMDAAFEFITKIGMPYYCFHDVDVVDYTDNVA
ENERRLQTMVEYAQQKQQETGVKLLWGTANVFSHSRYMNGASTNPDFHVLTHAAAQVKAA
LDATIALNGENYVFWGGREGYMTLLNTNMKREQEHFAKFLHTAKDYARKQGFKGTFFIEP
KPMEPTKHQYDYDAATVIGFLRQYDLLDDFKLNIEVNHATLAGHTFQHELQVASDAGLLG
SIDANRGDYQNGWDTDQFPNNLNELTEAMLVFLDAGGVKGGGINFDAKIRRNSTDPADLF
YAHIGGADTFARALITADNILQKSDYRKIREERYASFDSGKGKAFEEGKLSLEDLRNYAA
EQGEPEVRSGRQEYLENLINRYI