Protein Info for CA264_13390 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: sodium-translocating pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 754 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 57 to 75 (19 residues), see Phobius details amino acids 82 to 105 (24 residues), see Phobius details amino acids 126 to 157 (32 residues), see Phobius details amino acids 241 to 260 (20 residues), see Phobius details amino acids 275 to 298 (24 residues), see Phobius details amino acids 311 to 331 (21 residues), see Phobius details amino acids 345 to 369 (25 residues), see Phobius details amino acids 390 to 440 (51 residues), see Phobius details amino acids 486 to 508 (23 residues), see Phobius details amino acids 519 to 544 (26 residues), see Phobius details amino acids 585 to 603 (19 residues), see Phobius details amino acids 615 to 635 (21 residues), see Phobius details amino acids 689 to 707 (19 residues), see Phobius details TIGR01104: V-type H(+)-translocating pyrophosphatase" amino acids 6 to 705 (700 residues), 895.6 bits, see alignment E=1.4e-273 PF03030: H_PPase" amino acids 14 to 701 (688 residues), 893.6 bits, see alignment E=4.6e-273

Best Hits

KEGG orthology group: K01507, inorganic pyrophosphatase [EC: 3.6.1.1] (inferred from 76% identity to mtt:Ftrac_0768)

Predicted SEED Role

"Pyrophosphate-energized proton pump (EC 3.6.1.1)" in subsystem Phosphate metabolism (EC 3.6.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.1

Use Curated BLAST to search for 3.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YU10 at UniProt or InterPro

Protein Sequence (754 amino acids)

>CA264_13390 sodium-translocating pyrophosphatase (Pontibacter actiniarum KMM 6156, DSM 19842)
METILYAIPAFGLAALIYTGIRSAWVTKQPSGNERMSSIARHIADGAMAFLKAEYKVLAY
FVIIASLFLAYLGYTGEKSHPLIVGAFIVGACFSALAGFIGMRIATKANVRTAEAARSSL
SRALKVSFAGGSVMGMGVAGLAVLGLGSLFILFYFLFVVSPGADVHGVQMEIALEVLTGF
SLGAESIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAG
MGADLFGSYVATILATMVLGREVEVADNFGGLSPIILPMLIAGLGIVFSFIGMLFVRVSE
GGDVQAALNRGNWISVLLTAVASYFVIVWLLPENLVLRNFEFTELGVFMAVIVGLIVGSL
MSIITEYYTAMGKKPVNSIVQQSSTGHATNIIAGLAVGMHSTVLPIIVLAAGIVLSYAAA
GLYGVAIAAAGMMATTAMQLAIDAFGPIADNAGGIAEMSELPKEVRERTDILDAVGNTTA
ATGKGFAIASAALTSLALFAAFVGIAGIRTIDLYKAPVLAGLFIGAMIPFIFSALAISAV
GRAAMAMVQEVRRQFREIPGIMEGTGQPEYDKCVAISTQAAIREMMLPGAIALIVPLIVG
FGFRGVFPDTSSPEILGGLLAGVTVSGVLMAMFQSNAGGAWDNAKKSFEKGVMINGVMEY
KGSDPHKASVTGDTVGDPFKDTSGPSMNILIKLMSIVSLVIAPHIGLEQEPAIPEAPIEL
EPINLNRGEAAPGTASASINAPNTVALSFVGAAK