Protein Info for CA264_13270 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: tRNA lysidine(34) synthetase TilS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 TIGR02432: tRNA(Ile)-lysidine synthetase" amino acids 20 to 200 (181 residues), 186 bits, see alignment E=6.7e-59 PF01171: ATP_bind_3" amino acids 20 to 197 (178 residues), 179.5 bits, see alignment E=8.8e-57 PF11734: TilS_C" amino acids 365 to 434 (70 residues), 36.7 bits, see alignment E=3.2e-13 TIGR02433: tRNA(Ile)-lysidine synthetase, C-terminal domain" amino acids 366 to 409 (44 residues), 49.2 bits, see alignment 2.8e-17

Best Hits

KEGG orthology group: None (inferred from 42% identity to lan:Lacal_2238)

Predicted SEED Role

"tRNA(Ile)-lysidine synthetase (EC 6.3.4.19)" (EC 6.3.4.19)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.4.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YTT8 at UniProt or InterPro

Protein Sequence (443 amino acids)

>CA264_13270 tRNA lysidine(34) synthetase TilS (Pontibacter actiniarum KMM 6156, DSM 19842)
MLQKVSGFIQSHGLCQPGSKILAAVSGGIDSTVLCEVLHQLKYDFAVAHCNFGLRAEEAE
ADQLFVKKLAKKYDVPFFTENFNTRAFAEQEKLSTQMAARTLRYEWFEQVRQQEGYDLIA
TAHHSNDLTETILLHLTKGTGIAGLHGIPARNGSIIRPLLSITKDDIYEYVTERKLIWRE
DSSNETTKYQRNKIRHEVIPVLKEINPSLEETMQHSAERVSHAESIVAAYIAALRQQSVR
EAEEAVYVALEPLQNANGLPVVLHELLRPYNFSYSVVLELVEALEGIPGKQFESPTHTLV
KDRDQLVITQRNLSSFGSILINEGDTEAEAGGYSFSIKYIAADKYKLNTKPHVAALDAAQ
LKFPLKLRSWQEGDWFVPLGMNGKKKISDFLIDKKVPANLKSQTLVLVSDQSIAWIVGQR
LDNRFKVSDKTEQVVEITLGRKM