Protein Info for CA264_13165 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: arylesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 33% identical to ESTE_VIBMI: Arylesterase from Vibrio mimicus

KEGG orthology group: K10804, acyl-CoA thioesterase I [EC: 3.1.1.5 3.1.2.-] (inferred from 53% identity to phe:Phep_1599)

Predicted SEED Role

"Arylesterase precursor (EC 3.1.1.2)" (EC 3.1.1.2)

MetaCyc Pathways

phospholipid remodeling (phosphatidylethanolamine, yeast) (2/4 steps found)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.2, 3.1.1.5, 3.1.2.-

Use Curated BLAST to search for 3.1.1.2 or 3.1.1.5 or 3.1.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YYG5 at UniProt or InterPro

Protein Sequence (183 amino acids)

>CA264_13165 arylesterase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKNILIFGDSLTAGYGLPASQAYPSLIQERLKQEGYTAYKVLNGGLSGDTTAGGTHRIDR
WVNEPIDIFILALGANDGLRGIPTRETSQNLQEIISKVRNKCPEVKIILSGMEIPDIVPG
RYAAEFRKLFRELALENNVHFIPFLLEGVAGNRQLNLPDGVHPNAEGQKLLAQHTWSKLK
ELL