Protein Info for CA264_13100 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: 3-phosphoshikimate 1-carboxyvinyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00275: EPSP_synthase
  • amino acids 12 to 60 (49 residues), 30.3 bits, 9.5e-12
  • amino acids 63 to 398 (336 residues), 226.7 bits, E=2.3e-71

Best Hits

Swiss-Prot: 52% identical to AROA_BACFR: 3-phosphoshikimate 1-carboxyvinyltransferase (aroA) from Bacteroides fragilis (strain YCH46)

KEGG orthology group: K00800, 3-phosphoshikimate 1-carboxyvinyltransferase [EC: 2.5.1.19] (inferred from 55% identity to chu:CHU_0717)

Predicted SEED Role

"5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)" in subsystem Chorismate Synthesis or Common Pathway For Synthesis of Aromatic Compounds (DAHP synthase to chorismate) (EC 2.5.1.19)

MetaCyc Pathways

• superpathway of aromatic amino acid biosynthesis (17/18 steps found)
• superpathway of L-tryptophan biosynthesis (13/13 steps found)
• superpathway of L-phenylalanine biosynthesis (10/10 steps found)
• chorismate biosynthesis I (7/7 steps found)
• superpathway of L-tyrosine biosynthesis (9/10 steps found)
• chorismate biosynthesis from 3-dehydroquinate (5/5 steps found)
• chorismate biosynthesis II (archaea) (8/12 steps found)
• superpathway of chorismate metabolism (39/59 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Phenylalanine, tyrosine and tryptophan biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.19

Sequence Analysis Tools

See A0A1X9YTQ6 at UniProt or InterPro

Protein Sequence (410 amino acids)

>CA264_13100 3-phosphoshikimate 1-carboxyvinyltransferase (Pontibacter actiniarum KMM 6156, DSM 19842)
MSQSLTLSHPSGVLNGSIKLPASKSEANRALIIAALSGQESQLHNLSEANDTQLLQRLLK
SDAETIDAEDAGTVMRFLTAFYAITGQQKTLTGTERMCQRPIKVLVEALQELGASIEYLG
EEGYPPLKIGKFSGSGKKQLKVRSDISSQYISALLMVAPLLPEGLELELEGKIGSRPYIE
MTLSLMQHFGVSADFTENTITVKPQQYTSAAFTVESDWSAASYWYSLVALSKEADITLLG
LKEQSFQGDRAVVDIMYRLGVYTEFTGEGVRLLKKEHERHLSLDFSDCPDLAQTVVALCA
GLGIHLDMTGLESLRIKETDRIQALQIEVLSMNSSLQEISPGVFHLEPGILHKEQLSFRT
YQDHRMAMAFAPLALLEPVEIQEPSVVRKSYPRYWEDLGKVGFEVVMQQE