Protein Info for CA264_12540 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: glycoside hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00722: Glyco_hydro_16" amino acids 86 to 280 (195 residues), 105.3 bits, see alignment E=2.8e-34

Best Hits

Swiss-Prot: 58% identical to GUB_RHOMR: Beta-glucanase (bglA) from Rhodothermus marinus

KEGG orthology group: None (inferred from 69% identity to cpi:Cpin_6737)

Predicted SEED Role

"Beta-glucanase precursor (EC 3.2.1.73)" in subsystem Beta-Glucoside Metabolism (EC 3.2.1.73)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.73

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YTR2 at UniProt or InterPro

Protein Sequence (288 amino acids)

>CA264_12540 glycoside hydrolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MLSLYNKSLLLLSAFCAVLSCCSCSKSESPKPVITTPTAPTDKNWTFETTPAWADEFDYN
GLPDKSKWSYDIGGTGWGNNELQYYSDRASNASVANGILSITARKENMEGKGYTSARLIT
KGQGDFLYGRFEIRAKLPTGRGTWPAIWMLPTDWAYGSWPKSGEIDIMEHVGYDQNKVHI
TVHTDAYNHSKGTQKGNSKVIPTASTEFHVYRVDWTPYAVRGYIDNQPVFEYTNEGKGFT
SWPFDKRFHLLLNVAVGGDWGGAEGVDASVFPQTMEVDYVRVYKMKSA