Protein Info for CA264_11915 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: peptidoglycan synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 PF01225: Mur_ligase" amino acids 8 to 107 (100 residues), 38.4 bits, see alignment E=1.3e-13 PF08245: Mur_ligase_M" amino acids 114 to 288 (175 residues), 52.7 bits, see alignment E=5.7e-18

Best Hits

KEGG orthology group: K02558, UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC: 6.3.2.-] (inferred from 58% identity to chu:CHU_1348)

Predicted SEED Role

"Cytoplasmic peptidoglycan synthetase, N-terminal precursor"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.3.2.-

Use Curated BLAST to search for 6.3.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YT94 at UniProt or InterPro

Protein Sequence (461 amino acids)

>CA264_11915 peptidoglycan synthetase (Pontibacter actiniarum KMM 6156, DSM 19842)
MEKKDFQHIHLIAMGGSIMHNLALALHDKGLKVTGSDDEIYEPAKSRLAAAGILPEQEGW
FPEKLDAGPDAVILGMHARADNPELLRAQELNLPIYSFPEFIYEQSRDKQRVVIGGSHGK
TSITSMIMHVLQHIGRKFDYAVGAQLEGFDRMVKLSDDAPVIIIEGDEYLSDPIKRVPKF
HLYHHHIGVISGISWDHINVFPDPDIYRDQFRIFAEMTPKAGTLIYNQDDEQVQLVSVPR
NPADISYIGYGVHEHSIRDGKTILHTKKDGDVAVQLFGEHNLRNINAAKEVCKKIGVKAH
DFYEALKTFKGAAKRLQKLGESATANIYRDFAHAPSKVRATTEAVKKQFPERTLVAVLEL
HTFSSLNKSFIPQYAGALDLADEPIVYFSPKTLEHKRMEMLTQEELKAAFKNPNLKVYTD
SETLQQHLLERSWQNANLLLMSSGTYNNINLEALTQAVLKA