Protein Info for CA264_11130 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: mechanosensitive ion channel protein MscS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 transmembrane" amino acids 14 to 36 (23 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 90 to 108 (19 residues), see Phobius details amino acids 138 to 159 (22 residues), see Phobius details amino acids 169 to 193 (25 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 187 to 253 (67 residues), 55.1 bits, see alignment E=3.3e-19

Best Hits

KEGG orthology group: None (inferred from 53% identity to shg:Sph21_0356)

Predicted SEED Role

"Putative transport system permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YSZ5 at UniProt or InterPro

Protein Sequence (362 amino acids)

>CA264_11130 mechanosensitive ion channel protein MscS (Pontibacter actiniarum KMM 6156, DSM 19842)
MEYLVKLYERFDNVFTGLAIVAAALILGIIAKKLLFKGLNLYNRRENPFLFKSLTQHLSG
PLTLFIPLLFVSIALPLLPYSESLLLGLRRLTETLDIIAFAWVLVKLTDVGRDLVRHKYA
VDKADNIRERRLITQLQFLRKLTVVIIIFIAVSLILLSFDPVRKLGTGLLTSAGVAGVVV
GFAAQTSLANLLAGLQIAFTQPIRLDDVLVVENEFGRVEEITLTYVVLKLWDNRRLILPL
NYFIQNPFQNWTRTGSDLLATVYLYTDYTVPIEPLRKELDRILSKTDLWDKRVSVLQVTD
SKERTLELRALMSAHNSGIAWDLRCHVREKLVSFIQLNYPEALPKTRSEFAGQKLPPLAE
LS