Protein Info for CA264_10845 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: phospho-N-acetylmuramoyl-pentapeptide- transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 75 to 93 (19 residues), see Phobius details amino acids 99 to 116 (18 residues), see Phobius details amino acids 136 to 152 (17 residues), see Phobius details amino acids 210 to 229 (20 residues), see Phobius details amino acids 239 to 259 (21 residues), see Phobius details amino acids 279 to 296 (18 residues), see Phobius details amino acids 303 to 323 (21 residues), see Phobius details amino acids 329 to 351 (23 residues), see Phobius details amino acids 384 to 403 (20 residues), see Phobius details PF10555: MraY_sig1" amino acids 70 to 82 (13 residues), 22.8 bits, see alignment (E = 4.8e-09) PF00953: Glycos_transf_4" amino acids 102 to 324 (223 residues), 98.9 bits, see alignment E=3.1e-32 TIGR00445: phospho-N-acetylmuramoyl-pentapeptide-transferase" amino acids 214 to 406 (193 residues), 250 bits, see alignment E=2.1e-78

Best Hits

Swiss-Prot: 62% identical to MRAY_GRAFK: Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) from Gramella forsetii (strain KT0803)

KEGG orthology group: K01000, phospho-N-acetylmuramoyl-pentapeptide-transferase [EC: 2.7.8.13] (inferred from 68% identity to sli:Slin_4740)

Predicted SEED Role

"Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13)" in subsystem Peptidoglycan Biosynthesis (EC 2.7.8.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YSP8 at UniProt or InterPro

Protein Sequence (406 amino acids)

>CA264_10845 phospho-N-acetylmuramoyl-pentapeptide- transferase (Pontibacter actiniarum KMM 6156, DSM 19842)
MLYHLFTYLDREFDLFGAGVFQYISFRAGMATLVSLLIAMIFGGKLIKILQRKQVGESIR
DLGLEGQMEKKGTPTMGGLIILMAILVPVLLFARLDNVYVQLMLVSTVWLGLIGFLDDYI
KVFRKNKEGLAGRFKILGQIGLGLIVGLTLYFNDDVVVRQYLFSDGSTSAVNASNRYMDV
HSMITTIPFRKNNELDYCNLFSFAGPLFEGWSCYLYIPFVILVITAVSNGANITDGIDGL
AAGTSAIIGTTLAIFTYVSGNTIFADYLDIMFIPNSGELAIFCLAFVGGCVGFLWYNTYP
AQVFMGDTGSLSIGGIIAVLALIVRKELLIPILCGIFLVENLSVMLQVSYFKYTKKKYGE
GRRIFKMSPLHHHYQKLGYHESKIVGRFWIVGIMLAILTLATLKLR