Protein Info for CA264_09110 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: mechanosensitive ion channel protein MscS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 83 to 113 (31 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 101 to 175 (75 residues), 46.8 bits, see alignment E=1.3e-16

Best Hits

KEGG orthology group: None (inferred from 42% identity to mtt:Ftrac_0318)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YY08 at UniProt or InterPro

Protein Sequence (306 amino acids)

>CA264_09110 mechanosensitive ion channel protein MscS (Pontibacter actiniarum KMM 6156, DSM 19842)
MHELTQWLAGHSALPQDFYGRLFYSLAVIGVLWLLSRLLLRLVRQRLTDLRKQYQWRKFT
NYTATGLAILFLSYIWFDGFRSIATFLGLLSAGLVLALREPVLNMAGWVFIIWKRPFRIG
DRIQVGEHIGDVIDTRLFQFSLNEVQGWVKADQATGRVVNIPNLKVFTETQANYNYGFPF
IWQEIPVRITFESNWQKAKTILRDIMQRHAEQLTEAARQQIKRQSQRHLIFYEDLQPRLY
TTVCDNGIELTMRYVCSLMRRRQSAHLVWEDVLTEFLSSPDIRFAYPTTRFYQGGGEGQE
PLPEQV