Protein Info for CA264_09015 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 PF02771: Acyl-CoA_dh_N" amino acids 5 to 111 (107 residues), 55.9 bits, see alignment E=1.1e-18 PF02770: Acyl-CoA_dh_M" amino acids 116 to 212 (97 residues), 69.2 bits, see alignment E=5.5e-23 PF00441: Acyl-CoA_dh_1" amino acids 242 to 376 (135 residues), 68.1 bits, see alignment E=2e-22 PF08028: Acyl-CoA_dh_2" amino acids 243 to 360 (118 residues), 51.6 bits, see alignment E=2.4e-17

Best Hits

KEGG orthology group: None (inferred from 54% identity to hdn:Hden_0727)

Predicted SEED Role

"Butyryl-CoA dehydrogenase (EC 1.3.99.2)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases or Butanol Biosynthesis or Isobutyryl-CoA to Propionyl-CoA Module or Isoleucine degradation or Valine degradation (EC 1.3.99.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.2

Use Curated BLAST to search for 1.3.99.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YRR7 at UniProt or InterPro

Protein Sequence (384 amino acids)

>CA264_09015 acyl-CoA dehydrogenase (Pontibacter actiniarum KMM 6156, DSM 19842)
MSLEKVLNQIKDIAEGVVREEAVAVDREAWWPEKSMRTFQREGLGGFVVPKESGGLGQGL
YGLAQACETIGQESASTGLCFGMHCVGSAMIAAKATSHQKEHFLERIAAGEHLTTLALSE
PGTGAHFYYPQTQLLSVSENEFLLNGKKTFVTNGGKADSYVISTMGVDPEAAQYEFSCVV
VESDAQGLEWGPEWKGLGMRGNSSRSLALKDVKVPAANLLGEHGDQVWYVFQVVAPYFLT
AMSGTYLGVAQAALNEAREHLMQRTYSHSGISLSQNQLLQHRLGTLWAKVERTRRLIYHA
CQQYDSGDAMAVLGIISAKAEVATCVVEVVNEAMTLTGGIAYRESSRLEVLLRDARAAHI
MAPTTDILYTWLGRALLEQPILDS