Protein Info for CA264_08715 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: glucosamine-6-phosphate deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01182: Glucosamine_iso
  • amino acids 42 to 259 (218 residues), 74.6 bits, E=1.1e-24
• TIGR00502: glucosamine-6-phosphate deaminase
  • amino acids 44 to 277 (234 residues), 243.8 bits, E=9.8e-77
• PF02585: PIG-L
  • amino acids 376 to 551 (176 residues), 60.9 bits, E=1.8e-20

Best Hits

KEGG orthology group: K02564, glucosamine-6-phosphate deaminase [EC: 3.5.99.6] (inferred from 80% identity to zpr:ZPR_4699)

Predicted SEED Role

"Glucosamine-6-phosphate deaminase (EC 3.5.99.6)" in subsystem Chitin and N-acetylglucosamine utilization or Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 3.5.99.6)

MetaCyc Pathways

• N-acetylglucosamine degradation I (1/2 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis II (4/7 steps found)
• N-acetylglucosamine degradation II (1/3 steps found)
• chitin degradation I (archaea) (2/7 steps found)
• superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation (1/6 steps found)
• chitin derivatives degradation (1/8 steps found)
• superpathway of N-acetylneuraminate degradation (11/22 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.99.6

Sequence Analysis Tools

See A0A1X9YRM2 at UniProt or InterPro

Protein Sequence (654 amino acids)

>CA264_08715 glucosamine-6-phosphate deaminase (Pontibacter actiniarum KMM 6156, DSM 19842)
MQTLNSTVPFKSQNSMPRLNLLEETRFEKLPVSVFPDQHIASVSVAKRIADLIRDKQNKG
QQAVLGLATGATPVGVYAELVRMHREEGLSFRNVITFNLDEYYPMQPDAAQSYVTFMNEN
LFDHIDIEKANVHVPDGTLPKEEIHAYCLNYERQIEEVGGLDLQILGIGRTGHIGFNEPG
SAPNSGTRLVTLDDLTRRDAARDFGGKENVPTKAITMGIGTIFKAREIILMAWSQKKAPI
IKKAVEGEMSSEVPATYLQLSNSVEFVLDDDAASELTRFNTPWLVKDCVWDEQLTKKAVI
WLSEKLGKPILKLTDEDYNTHGMAQLATEFGPAYNINIDIFNKIQHTITGWPGGKPNADD
TQRPERAEPAQKRVIIFSPHPDDDVISMGGTFIRLVDQGHDVHVAYQTSGNTAVWDDDVL
RYMEFAIDFNKSIGSDTSRLRQIYDDMRGFIEEKQPNQVDTQEILNVKGFIRKSEAYAGA
RYAGLEDENIHFMALPFYETGKRKKNSVTDKDIELTMDLLQRVKPQQVFAAGDFADPHGT
HIVCFKIVVEALQRLRQTEEWANDCWLWMYRGAWHEFETHEIEMAVPLSPQEVIRKREAI
FKHQSQKDRPVFPGDDAREFWVRAEERNRETAENYHKLGLADYEAMEAFVRYNF