Protein Info for CA264_07595 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 546 transmembrane" amino acids 518 to 535 (18 residues), see Phobius details PF01627: Hpt" amino acids 7 to 96 (90 residues), 39.5 bits, see alignment E=1.1e-13 PF02895: H-kinase_dim" amino acids 152 to 209 (58 residues), 47.2 bits, see alignment 4.9e-16 PF02518: HATPase_c" amino acids 259 to 396 (138 residues), 66 bits, see alignment E=8e-22 PF01584: CheW" amino acids 403 to 537 (135 residues), 81.5 bits, see alignment E=9.5e-27

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YR39 at UniProt or InterPro

Protein Sequence (546 amino acids)

>CA264_07595 chemotaxis protein CheA (Pontibacter actiniarum KMM 6156, DSM 19842)
MKSREQEYKEIFIAEALEYFDALNRHISTLEKEPEDEQTLAEIFRLLHNLKANSKAIGYL
QISDVSHKLETAFSLIRNKELAFSEEVVTVLFDGIDMLGELIHNVDNPNYGEPDPVLLRN
LDIIVENLSDSTIELAKVQKYNTSKNLSLSELIYIQIKKLDHMMNLVGELMIDRDRILSI
SRDLNNDELKSVSSHLYRITEDLQYSVMDARLVNIGSLFNKFPRIVRDIATAEKKDVDLK
LTGQDIQIDRNILQIITDSLLHLVRNAITHGLETPEDRKKKGKEPVGNLTLSAQSDRDNV
VIRLQDDGKGIDLRKVKKTAVERQLVSADVAKGLADNELLSFLFEPGFSTAKEVTEYSGR
GVGLDVVKNAIDSIGGRISVDSEKGAGTTFILQLPTSIAVKGALLFEVDENYYAIPLIHT
DQVVALDKDELHEVGDVLIANLKGETVTVVYLNELLNAPEASMKLGDKTRLNGQVQNIII
VSYNNRKLGLIVDKLYRQQDIVVKPLSKPLEQIDIYGGVTLLGTGKVCLVLDVPAVTRYF
MSKRQA