Protein Info for CA264_07455 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 TIGR02009: beta-phosphoglucomutase family hydrolase" amino acids 13 to 221 (209 residues), 164 bits, see alignment E=4.4e-52 PF00702: Hydrolase" amino acids 13 to 217 (205 residues), 80.6 bits, see alignment E=3.2e-26 PF13419: HAD_2" amino acids 17 to 217 (201 residues), 60.5 bits, see alignment E=3.5e-20 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 139 to 222 (84 residues), 47.4 bits, see alignment E=2.4e-16

Best Hits

Swiss-Prot: 41% identical to Y3400_MYCTU: Uncharacterized protein Rv3400 (Rv3400) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 46% identity to tfu:Tfu_3043)

Predicted SEED Role

"Beta-phosphoglucomutase (EC 5.4.2.6)" in subsystem Maltose and Maltodextrin Utilization or N-Acetyl-Galactosamine and Galactosamine Utilization or Trehalose Uptake and Utilization (EC 5.4.2.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YQY8 at UniProt or InterPro

Protein Sequence (258 amino acids)

>CA264_07455 hydrolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MSDLNKLIKERNIKALILDMDGVVTNTAGLHAEAWKKLCDSFLRQRREEGGDEYKPFDLK
EDYRTYVHDVPRLDAMRNFMESRGVFLPEGEPDDDADKNTIVGLGERKDLYFHELLKQDG
VVVFDKAVQWIKEQKQAGMKVAIVSASRNCLTILRRAGLEKLFEARVDKVVAAELKLNNK
PAPDVYLEAARRLGAAPQEAAVFEDSEAGIEGAKAGGFGLVVGVDHSYKKEVFEMRGADI
VIKGFSSEVKAKSESTLS