Protein Info for CA264_07100 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: PrkA family serine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 642 PF08298: AAA_PrkA" amino acids 18 to 377 (360 residues), 564.3 bits, see alignment E=1.1e-173 PF06798: PrkA" amino acids 379 to 633 (255 residues), 219.6 bits, see alignment E=5.8e-69

Best Hits

Swiss-Prot: 66% identical to YEAG_ECO57: Uncharacterized protein YeaG (yeaG) from Escherichia coli O157:H7

KEGG orthology group: K07180, serine protein kinase (inferred from 70% identity to cvi:CV_1789)

MetaCyc: 66% identical to protein kinase YeaG (Escherichia coli K-12 substr. MG1655)
2.7.11.d,2.7.11.11,2.7.12.1,2.7.11.12,2.7.11.17,2.7.11.1,2.7.11.13,2.7.11.22,2.7.11.21,2.7.11.34,2.7.11.31 [EC: 2.7.11.1, 2.7.11.11, 2.7.11.12, 2.7.11.13, 2.7.11.17, 2.7.11.21, 2.7.11.22, 2.7.11.31, 2.7.11.34, 2.7.11.d, 2.7.12.1]

Predicted SEED Role

"Serine protein kinase (prkA protein), P-loop containing"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.1

Use Curated BLAST to search for 2.7.11.1 or 2.7.11.11 or 2.7.11.12 or 2.7.11.13 or 2.7.11.17 or 2.7.11.21 or 2.7.11.22 or 2.7.11.31 or 2.7.11.34 or 2.7.11.d or 2.7.12.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YQR7 at UniProt or InterPro

Protein Sequence (642 amino acids)

>CA264_07100 PrkA family serine protein kinase (Pontibacter actiniarum KMM 6156, DSM 19842)
MNILEKIKTNYSASMNEMTVAAYLEECKKDPSVYAKPAERILHAIGEPEVLDTRQDPVLS
RIFSNKKIKVYPAFKDFYGMESTIEQIVSYFRHSAQGLEEKKQILYLMGPVGGGKSSLAE
KLKHLMQQNPIYVLKAGEEVSPVFESPLGLFADYTEELEEEYSIPSRYVPSCMSPWASKR
LREFDGDINRFKVIRLFPSIQDQVAISKTEPGDENNQDISTLVGKVDIRKLAEYQQSDPD
AYSYTGGLCLANQGLLEFVEMFKAPIKVLNPLLTATQEKNYKGTEPIGAIPFDGIILAHS
NESEWAKFLNDKKNEAFLDRIYKVQVPYCLRVSEEIKIYEKLIRESSLKNAPCAPKTIEL
LAEFSVMSRLKEPENSSIYSKMRVYNGETLKETDPNAKSIQEYRDDAGINEGMQGISTRF
AFKILSKVFNFDSEEIAANPVHLLYVLEQEVVKMMLPPETETKYLHLIKSLLASKYAEFI
ADEIQKAYIESYSSYGQNIFEKYVIYADHWMQNNDYRDPDSGEIFDRSILNAELEKIEKP
AGIANPKDFRAEVTNFTLRYKANHGGENPRWDSYEKIKNVIEKKIFTNTEDLLPVVSFTA
KSNKEDEKKHRDFTKRMKDRGYTDKQIRILVDWFMRVRKTMA