Protein Info for CA264_06625 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: tRNA modification GTPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 459 PF10396: TrmE_N" amino acids 10 to 126 (117 residues), 145.4 bits, see alignment E=3e-46 TIGR00450: tRNA modification GTPase TrmE" amino acids 15 to 459 (445 residues), 405.5 bits, see alignment E=3.5e-125 PF12631: MnmE_helical" amino acids 129 to 456 (328 residues), 186.6 bits, see alignment E=2.4e-58 PF00025: Arf" amino acids 223 to 361 (139 residues), 25.5 bits, see alignment E=3e-09 PF01926: MMR_HSR1" amino acids 226 to 339 (114 residues), 90.4 bits, see alignment E=3.1e-29 TIGR00231: small GTP-binding protein domain" amino acids 226 to 371 (146 residues), 90.7 bits, see alignment E=8.8e-30 PF00071: Ras" amino acids 226 to 353 (128 residues), 25 bits, see alignment E=4.6e-09 PF02421: FeoB_N" amino acids 226 to 348 (123 residues), 35.3 bits, see alignment E=3e-12

Best Hits

Swiss-Prot: 62% identical to MNME_CYTH3: tRNA modification GTPase MnmE (mnmE) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)

KEGG orthology group: K03650, tRNA modification GTPase (inferred from 62% identity to chu:CHU_2030)

Predicted SEED Role

"GTPase and tRNA-U34 5-formylation enzyme TrmE" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YQL9 at UniProt or InterPro

Protein Sequence (459 amino acids)

>CA264_06625 tRNA modification GTPase (Pontibacter actiniarum KMM 6156, DSM 19842)
MIHTDFSNDTIVAVATAPGVGAIAVIRLSGPEAISITNSVFKGKDLARQACHTIHFGTIR
EEEKVLDEVLVSLFVAPHSYTKENVVEISCHGSDYIVQQIVQLLLKRGARLANAGEFTKR
AFLNGQFDLAQAEAVADLISSDSALSHEVAMKQMRGGFSQEIKRLRAELVHFASMIELEL
DFGEEDVEFADREQLRTLISNIQRIIRELLKSFELGNVIKNGVPTVIVGNPNAGKSTLLN
KLLNEEKAIVSDVPGTTRDFIEDEINIEGITFRFIDTAGLRETTDKVEAIGVERTMQKLS
QSSLIIYLFDITEVTAAQVQAELDRLNPKKLPLVAVANKIDRAPADKVAAFESIEGLVTI
SAAEGANLDELKQALVEKVNLGKLNTQSQTIVTNLRHVDSLNKTYAALDDVLNGLGLGMS
GDLVAADIRRALYSLGEITGEITTDDLLDNIFTKFCIGK