Protein Info for CA264_05985 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: MBL fold hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 PF00753: Lactamase_B" amino acids 22 to 203 (182 residues), 49.6 bits, see alignment E=1.2e-16 PF16661: Lactamase_B_6" amino acids 25 to 174 (150 residues), 34.9 bits, see alignment E=2.5e-12 PF12706: Lactamase_B_2" amino acids 33 to 102 (70 residues), 27.4 bits, see alignment E=6.3e-10 PF10996: Beta-Casp" amino acids 257 to 378 (122 residues), 115.3 bits, see alignment E=6e-37 PF07521: RMMBL" amino acids 393 to 454 (62 residues), 62.5 bits, see alignment E=8e-21

Best Hits

KEGG orthology group: K07576, metallo-beta-lactamase family protein (inferred from 44% identity to rbi:RB2501_04830)

Predicted SEED Role

"Metallo-beta-lactamase family protein, RNA-specific" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YQ82 at UniProt or InterPro

Protein Sequence (463 amino acids)

>CA264_05985 MBL fold hydrolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MAQQSGPVQLQFLGAAGVVTGSRTLLQIGDLKLLVDCGLFQGNKKERKLNKAKRFPFKPS
ELDAILLTHGHLDHSGYLPVLVKKGYSGPIYATAPTKDITEVILTDSAHIQQEDAKDLNQ
RRAEAGKKPVKPLYRPKHVRRTMELFQTYTDQEWVTLKEGVKFRFLKSGHILGSASIELV
CDGKTYLFSGDIGQQEPLILDSPTRCVRADYVVLESTYGDKLHDKSNSPFQALQEVVNST
FEKGGSVVIPSFAVERAQEIIMLLNDLRREKSIPAIPIYLDSPMGINITELFQKYKGWHN
LSDAEAEDLTDNVHIIKSFEDTLHVLDEDSPKQKIIIAGSGMATGGRVLYYLKKLVGDEK
NTILLVGHQAKGTRGNKLSKGASEIKIDGQRFPVRADIRQIGSLSAHADQEDLLWCLSAM
RAAPERVFLNHGEQDATVALKEKIEQQYGWPVSIAKMDKVYHL