Protein Info for CA264_05825 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: isoaspartyl peptidase/L-asparaginase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01112: Asparaginase_2
  • amino acids 5 to 307 (303 residues), 390.7 bits, E=2.2e-121

Best Hits

Swiss-Prot: 52% identical to IAAA_ECOLI: Isoaspartyl peptidase (iaaA) from Escherichia coli (strain K12)

KEGG orthology group: K13051, beta-aspartyl-peptidase (threonine type) [EC: 3.4.19.5] (inferred from 60% identity to gfo:GFO_0747)

MetaCyc: 52% identical to isoaspartyl dipeptidase proenzyme (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Isoaspartyl aminopeptidase (EC 3.4.19.5) @ Asp-X dipeptidase" (EC 3.4.19.5)

MetaCyc Pathways

• cyanophycin metabolism (6/6 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.4.19.5

Use Curated BLAST to search for 3.4.19.5

Sequence Analysis Tools

See A0A1X9YQ34 at UniProt or InterPro

Protein Sequence (311 amino acids)

>CA264_05825 isoaspartyl peptidase/L-asparaginase (Pontibacter actiniarum KMM 6156, DSM 19842)
MNNIAIAIHGGAGTITQATLSEEQDQAYRAALREAVEAGYALLAQGATAVEAVELAVVHL
EDTPLFNAGKGSVFTKEGKHEMDAAIMCGKDLQAGAVAGVHRIKNPVRLAKTIMQHSDHV
MLSGYGAEDFALLHQLEFAPENYFFDKYRYEQWSEVRDTNIFMLDHTEQRDEKFGTVGAV
AVDSNGDVAAATSTGGMTNKSYNRIGDTPIIGSGTYANNRTCAISCTGHGEYFMRAVVAY
DVSCLMEYKGYSLEKACEEVVMRKLVDFGGEGGLIAVNAAGEVAMPFNSEGMYRASKSQD
QETFVAIYKES