Protein Info for CA264_05780 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: cytochrome C oxidase Cbb3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 730 transmembrane" amino acids 39 to 61 (23 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 151 to 171 (21 residues), see Phobius details amino acids 179 to 199 (21 residues), see Phobius details amino acids 226 to 248 (23 residues), see Phobius details amino acids 258 to 276 (19 residues), see Phobius details amino acids 294 to 316 (23 residues), see Phobius details amino acids 328 to 344 (17 residues), see Phobius details amino acids 364 to 387 (24 residues), see Phobius details amino acids 406 to 424 (19 residues), see Phobius details amino acids 456 to 477 (22 residues), see Phobius details amino acids 519 to 540 (22 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 31 to 493 (463 residues), 674.4 bits, see alignment E=9.5e-207 PF00115: COX1" amino acids 34 to 465 (432 residues), 395 bits, see alignment E=4.5e-122 TIGR00781: cytochrome c oxidase, cbb3-type, subunit II" amino acids 509 to 726 (218 residues), 260.5 bits, see alignment E=1.5e-81 PF02433: FixO" amino acids 509 to 722 (214 residues), 335.2 bits, see alignment E=1.6e-104

Best Hits

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] K00405, cb-type cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 75% identity to sli:Slin_3562)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1) / Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YQ84 at UniProt or InterPro

Protein Sequence (730 amino acids)

>CA264_05780 cytochrome C oxidase Cbb3 (Pontibacter actiniarum KMM 6156, DSM 19842)
MSTNVAEVLENAPDRVVPKGKDPGATDTFFYDNKIVRDFGIATVFWGIAGMLIGTLIAFQ
LARPELNMGTQYTTFGRIRPLHTNAVIFAFVGNAIFMGVYYSLQRLCKTRMYSDWLSKIN
FWGWQLIIVSAVITLPLGFTTSKEYAELEWPIDIAITLIWVVFGWNMFGTIAKRREKHLY
VAIWFYIATFLTVAVLHIVNSYEMPVNFLKSYSGYAGVQDALVQWWYGHNAVAFFLTTPF
LGLMYYFLPKAANRPVYSYRLSIIHFWSLIFIYIWAGPHHLLYTSLPDWAQSLGVVFSVM
LLAPSWGGMINGLLTLRGAWDKVRENPILKFMVVAITAYGMATFEGPMLSLKNVNAIAHF
TDWIVAHVHVGALGWNGFLTFAMLYWLFPRLYKTPLYSVKLANTHFWLGTLGILFYAIPM
YWAGFTQGLMWKQFSEEGMLQYPNFLETVLQIVPMYYLRGIGGVLYLSGVFLMVYNLIKT
AKSGKLVANERTEAPVVVPTASNNAGHWHSWIEKRPTQMAIFATVAILIGGLVEFIPTFV
IKSNVPTIASVKPYTSLELQGRDLYIKEGCVNCHTQMVRPFRSETERYGEYSKAGEFVYD
HNFLWGSKRTGPDLHRVGGKYPHSWHYHHMMDPTSMSPGSIMPAYPWLFEQEIDQSTTQA
KLETLKKLGVPYEEEYIANANEELMEQARGISADLAKEGLEVKPEKEIVALIAYLQRLGT
DIKVKTEEVE