Protein Info for CA264_05320 in Pontibacter actiniarum KMM 6156, DSM 19842
Annotation: para-aminobenzoate synthase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Para-aminobenzoate synthase, aminase component (EC 2.6.1.85)" in subsystem Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. or Folate Biosynthesis (EC 2.6.1.85)
MetaCyc Pathways
- superpathway of tetrahydrofolate biosynthesis and salvage (10/12 steps found)
- L-citrulline biosynthesis (7/8 steps found)
- glutaminyl-tRNAgln biosynthesis via transamidation (4/4 steps found)
- L-glutamate and L-glutamine biosynthesis (6/7 steps found)
- ammonia assimilation cycle III (3/3 steps found)
- superpathway of tetrahydrofolate biosynthesis (8/10 steps found)
- 4-aminobenzoate biosynthesis I (2/2 steps found)
- L-glutamate biosynthesis I (2/2 steps found)
- superpathway of L-citrulline metabolism (9/12 steps found)
- L-glutamine degradation I (1/1 steps found)
- L-asparagine biosynthesis III (tRNA-dependent) (3/4 steps found)
- superpathway of chorismate metabolism (39/59 steps found)
- superpathway of candicidin biosynthesis (4/11 steps found)
- chloramphenicol biosynthesis (1/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.85
Use Curated BLAST to search for 2.6.1.85
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1X9YPV4 at UniProt or InterPro
Protein Sequence (429 amino acids)
>CA264_05320 para-aminobenzoate synthase (Pontibacter actiniarum KMM 6156, DSM 19842) MVKTEILEKELPISLEEFRLKALAWADTYPLAAYYNPNNIPYPHQGFEHLLAVSGGAALP LNEADAFGSLRKTLLAPHPLLCGYLGYDLKNQVEKLSSHNHDGIGFPLLTFFVPDLYLYF NSESIRLYTSDRKANDIVAAICATATPAPATPAGIQVTQRVAREKYTRQVERIRQHILEG DVYELNFCMEFYAEQVQLQPLPLYLALNAASPTPFSGYLKLQDKYLLCASPERFMKKEGQ KLISQPIKGTIRRGSTPEEDKALQRQLRHDEKELAENMMIVDLVRNDLSRSCATGTVQVE EMFGIYGFRQVSQMISTIVGELRAEKDLTDALSGTFPMGSMTGAPKISAMQLIEELEDTR RGLYSGAFGYISGNGDCDFNVVIRSMQYNAGTGYLSFMVGSAITYDSDPNQEYEECLLKA QAILKVLGQ