Protein Info for CA264_05285 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: molecular chaperone GroEL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 TIGR02348: chaperonin GroL" amino acids 2 to 526 (525 residues), 867.4 bits, see alignment E=1.6e-265 PF00118: Cpn60_TCP1" amino acids 22 to 523 (502 residues), 285.8 bits, see alignment E=3.3e-89

Best Hits

Swiss-Prot: 83% identical to CH60_CYTH3: 60 kDa chaperonin (groL) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)

KEGG orthology group: K04077, chaperonin GroEL (inferred from 83% identity to chu:CHU_1828)

MetaCyc: 65% identical to chaperonin GroEL (Escherichia coli K-12 substr. MG1655)
Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10, 5.6.1.7]

Predicted SEED Role

"Heat shock protein 60 family chaperone GroEL" in subsystem GroEL GroES or Staphylococcal pathogenicity islands SaPI

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.4.10 or 5.6.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YPV9 at UniProt or InterPro

Protein Sequence (544 amino acids)

>CA264_05285 molecular chaperone GroEL (Pontibacter actiniarum KMM 6156, DSM 19842)
MAKNITFDTDARTKIKSGVDKLANAVKVTLGPKGRNVIIDKKFGAPTITKDGVSVAKEIE
LNDPIENMGAQLVKEVASKTADQAGDGTTTATVLAQAIYTAGIKNVAAGANPMDLKRGID
KAVEAVVANLKSQSKTIDNSSEIAQVGTISANNDPEIGKMIADAMDKVGKDGVITVEEAK
GTETEVKTVEGMQFDRGYLSPYFVTNAEKMEADFDNPYILIYDKKVSTMKELLPVLEQVV
QTGKGLVIVAEDVDGEALATLVVNKLRGSLKIAAVKAPGFGDRRKAMLEDIAILTGGTVI
SEERGYKLENATLDYLGQAEKVIIDKDNTTIVNGAGTKDDIVARVNQIKAQMETTTSDYD
KEKLQERLAKISGGVAILYIGASTEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIR
AIDALENLDVANEDQKTGIQIIRTAIESPLRTIVANAGGEGSVVVQAVREGKTDYGYNAR
DNKYENMFAAGIIDPTKVTRLALENAASIAGLLLTTECVVSEDPEEEKGAPAMPGGMGGM
GGMM