Protein Info for CA264_05065 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: anthranilate phosphoribosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF02885: Glycos_trans_3N" amino acids 2 to 63 (62 residues), 58.1 bits, see alignment E=6.2e-20 TIGR01245: anthranilate phosphoribosyltransferase" amino acids 6 to 328 (323 residues), 317.4 bits, see alignment E=6.1e-99 PF00591: Glycos_transf_3" amino acids 74 to 320 (247 residues), 232.7 bits, see alignment E=5.7e-73

Best Hits

Swiss-Prot: 65% identical to TRPD_GRAFK: Anthranilate phosphoribosyltransferase (trpD) from Gramella forsetii (strain KT0803)

KEGG orthology group: K00766, anthranilate phosphoribosyltransferase [EC: 2.4.2.18] (inferred from 65% identity to gfo:GFO_2670)

Predicted SEED Role

"Anthranilate phosphoribosyltransferase (EC 2.4.2.18)" in subsystem Auxin biosynthesis or Tryptophan synthesis (EC 2.4.2.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.2.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YPR8 at UniProt or InterPro

Protein Sequence (335 amino acids)

>CA264_05065 anthranilate phosphoribosyltransferase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKEILNHLFEHKTLTKEQAREVLVNIAGGKYNQSQISSFLTVFMMRSITVDELEGFRDAL
LALCHRVDLDAYNPIDLCGTGGDGKDTFNISTLSSFVVAANGVAVAKHGNYGVSSSCGSS
NVLEALGIKFTTDTDALERSIEKYNICFLHAPLFHPAMKSVGPIRKDLGVKTFFNMLGPM
VNPAFPKRQLVGVFSLELARMYGYLYQQTDTRYTILHTLDGYDEISLTSPFKVISDNREA
LLDAQALGLPTLQQEQIRGGGTIESAAEIFLKVLKGEGTEAQTAVVSANSAMALQCARPE
LELQEAVSIAKETLESGKAYALFNSLIQDKNLVVA