Protein Info for CA264_04855 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: alpha-amylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 PF00128: Alpha-amylase" amino acids 32 to 370 (339 residues), 355.1 bits, see alignment E=5.4e-110 PF11941: DUF3459" amino acids 439 to 518 (80 residues), 28.2 bits, see alignment E=2.1e-10

Best Hits

Swiss-Prot: 39% identical to MALT_AEDAE: Probable maltase (MAL1) from Aedes aegypti

KEGG orthology group: K01187, alpha-glucosidase [EC: 3.2.1.20] (inferred from 68% identity to dfe:Dfer_0107)

Predicted SEED Role

"Maltodextrin glucosidase (EC 3.2.1.20)" in subsystem Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YPM4 at UniProt or InterPro

Protein Sequence (533 amino acids)

>CA264_04855 alpha-amylase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKQEQQYLWWQSGIIYQVYPRSFQDSDGDGIGDLKGIIKRLDYLKWLGVTAVWVSPIYPS
PMADYGYDISDYCGIHPLFGTMEDFDALLQEVHKRDMKLILDLVPNHTSNEHPWFLESRS
SRDNPKRDWYIWEDPAEHGGEPNNWLSVFGGSGWEWDEKTEQYYYHAFLKEQPDLNWRNP
EVQQAMFDVMRFWLDKGVDGFRVDVMWHMIKDKKLRDNPPNPDYQQHESTYNQLIPAFST
DQPEVHDIVAMMRSVMDEYDERVMIGEIYLPIHRLVSYYGQDNSGAHLPFNFMLITLDWN
ALTLSSHIDEYEGALPKGGWPNWVIGNHDKPRITSRVGYSQAKIAGMLLLTLRGTPTLYY
GDELGMRDVPIPPEEVQDPQGLNMPDKDLSRDPARTPMQWDNSANAGFTDGKPWLRLPTN
FRRVNVEVQKEDQYSMLTFYHRLIHLRQQEAALNIGDYEPVLTKAPLLAFVRKTEEKQLL
VILNLSHKPCTFRPQGQRYKGTVVLATDPEREESTVEGNITLYGDEGILVALD