Protein Info for CA264_04770 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: metal-dependent hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 PF13483: Lactamase_B_3" amino acids 2 to 190 (189 residues), 82.3 bits, see alignment E=6.2e-27 PF00753: Lactamase_B" amino acids 7 to 174 (168 residues), 47.6 bits, see alignment E=3.1e-16 PF12706: Lactamase_B_2" amino acids 18 to 191 (174 residues), 84.4 bits, see alignment E=1.3e-27

Best Hits

Swiss-Prot: 55% identical to Y2312_GRAFK: UPF0173 metal-dependent hydrolase GFO_2312 (GFO_2312) from Gramella forsetii (strain KT0803)

KEGG orthology group: None (inferred from 54% identity to psn:Pedsa_3295)

Predicted SEED Role

"conserved protein YtkL"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YPM1 at UniProt or InterPro

Protein Sequence (226 amino acids)

>CA264_04770 metal-dependent hydrolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKITYYGQSCFLFEIGENRVLFDPFISPNELASSINVDDIKADYILLSHGHQDHVHDAEQ
IARNNNSTIIATFEITNWYGAKGLENLHPMNTGGKVTLPFGTVKMVNAVHSSSLPDGTYA
GTAAGFVVETENKTFYYAGDTALTYDMKLIPEQFDVDFALLPIGDNFTMDVHDAMIAADF
VQVDKVIGMHFDTFPYIKIDKEEVMEVAQMADKELILMEIGQTIEL