Protein Info for CA264_04700 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: cyanophycin synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 875 TIGR02068: cyanophycin synthetase" amino acids 2 to 865 (864 residues), 1116.1 bits, see alignment E=0 PF18921: Cyanophycin_syn" amino acids 25 to 137 (113 residues), 115.4 bits, see alignment E=7e-37 PF08443: RimK" amino acids 215 to 318 (104 residues), 29.4 bits, see alignment E=2.9e-10 PF02786: CPSase_L_D2" amino acids 216 to 300 (85 residues), 31.4 bits, see alignment E=7.1e-11 PF02222: ATP-grasp" amino acids 225 to 304 (80 residues), 29.4 bits, see alignment E=3e-10 PF07478: Dala_Dala_lig_C" amino acids 226 to 310 (85 residues), 24 bits, see alignment E=1.2e-08 PF02955: GSH-S_ATP" amino acids 235 to 321 (87 residues), 23.5 bits, see alignment E=1.7e-08 PF08245: Mur_ligase_M" amino acids 487 to 697 (211 residues), 101.3 bits, see alignment E=3.6e-32 PF02875: Mur_ligase_C" amino acids 722 to 798 (77 residues), 43.2 bits, see alignment E=2e-14

Best Hits

Swiss-Prot: 52% identical to CPHA_SYNY3: Cyanophycin synthetase (cphA) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K03802, cyanophycin synthetase [EC: 6.-.-.-] (inferred from 55% identity to fps:FP1111)

MetaCyc: 51% identical to cyanophycin synthase monomer (Thermosynechococcus vestitus BP-1)
Cyanophycin synthase (L-arginine-adding). [EC: 6.3.2.30]; Cyanophycin synthase (L-aspartate-adding). [EC: 6.3.2.30, 6.3.2.29]

Predicted SEED Role

"Cyanophycin synthase (EC 6.3.2.29)(EC 6.3.2.30)" in subsystem Cyanophycin Metabolism (EC 6.3.2.29, EC 6.3.2.30)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.-.-.-

Use Curated BLAST to search for 6.-.-.- or 6.3.2.29 or 6.3.2.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YPJ0 at UniProt or InterPro

Protein Sequence (875 amino acids)

>CA264_04700 cyanophycin synthetase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKIIDLRVMRGPNYWSVKHPKLIVIKLALEELSQKYTNEVPHFLSRLKKMFPGMQRHRAA
EGVEGGFFNAVAEGTTFGHVVQHVALELQTLAGMESGYGRCYPAHEEDHMTVVYSYQEER
AGEYAAYAAVRITRALVSGEKYRLSEDITRLHDIREDEYFGPSTYSIVSEAVSRGIPYIR
LNRHSLIQLGYGVNQKRIQATMTCKTACFSVEIAGDKNATKDILEEAGIPVPRGTTVSSQ
EELKRAISWLGYPIVIKPLDGNHGKGATINITNAKDAHKGFTEARKHSQLVMVEQYIQGF
DFRLLVINGKFVAAAKRTPAMVTGDGTSTIKQLIDRENRDPRRGIGHEKVLTRIKIDKHT
KNILKSLNLTTKSVLPVGEVLYLKSTANISTGGTATDVTDLVDPYNILMAERIAGLIGLD
VCGIDVMTSDIAIPLNETRGAVLEVNAAPGFRMHISPTFGLPRNVAEPVIDMLFPHGKPA
RVPIIAVTGTNGKTTTTRLIAHMVKHKGYQVGYTTTEGIYIQDKLLEKGDTTGSYSAEFV
LKDPTVNFAVLECARGGLLRAGLGFEQCDIGIVTNVSSDHLGLRDIYTLEDLAKVKAVIP
KSVSKDGYAVLNADDDLVYAMAEDVSCKVAFFSMDENNPRILKHIAKGGLAAVYENGYIS
IFKNSYKIRIDRVADVPLTFGGKAKFNIENILAATLAGYISHFEVEDIKTSLRTFIPSPS
KTPGRMNLFKFPNFEVLVDYAHNVGGLKAIGEYMDALEATKKVGIVAAVGDRRPEDFYEI
GQVAGQIFDEVIVRLDSDLRGKTADEIMGPVLQGIEDAAPEKAVHQIPEEMRAIAFALEH
AEPGSFIAIFTEDVHESVKMVESFKVIQDRKMFVE