Protein Info for CA264_04360 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: transketolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 802 PF00676: E1_dh" amino acids 42 to 353 (312 residues), 98.8 bits, see alignment E=4.5e-32 PF02779: Transket_pyr" amino acids 469 to 635 (167 residues), 74.8 bits, see alignment E=1.1e-24 PF02780: Transketolase_C" amino acids 658 to 747 (90 residues), 74.1 bits, see alignment E=1.5e-24

Best Hits

KEGG orthology group: None (inferred from 69% identity to mtt:Ftrac_3619)

Predicted SEED Role

"Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) / Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)" in subsystem Isoleucine degradation or Leucine Degradation and HMG-CoA Metabolism or Valine degradation (EC 1.2.4.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.2.4.4

Use Curated BLAST to search for 1.2.4.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YPD4 at UniProt or InterPro

Protein Sequence (802 amino acids)

>CA264_04360 transketolase (Pontibacter actiniarum KMM 6156, DSM 19842)
MQTAEASITQKLTAEEILSDYRIAWESRQASLTGRKEVFMGKAKFGIFGDGKEVAQLAMA
KFFRDGDFRSGYYRDQTFMFAIGELTLQQYFAQLYAHTDVEAEPSTAGRAMNGHFGTRSL
DEEGNWKNLTEQKNSSSDISPTAAQMPRLVGLAYASKLYRQNEGLQNLKNFSVNGNEVAF
GTIGNASTSEGMFFEAINAGGVLQVPMLVSVWDDAYGISVPAEYQTTKGSISEILAGFQR
TSQDGQGYEIFKVKGWDYAALCETYEAAVRVCREQHVPVLVHVEELTQPQGHSTSGSHER
YKSKERLEWEADYDCLKKMREWILSSDIASAEQLDQIEAEAKETVKSARGEAWNAFASAI
KADHEEALHLLDNLAAASEHITEVATITEELRKTTNPIRSDAVRAVRKALRYVRDENNQA
KRELVGWLEQAMGENADRFNSYLYSQSEEAALQIEEVKAEFDENSPVVDGREVLQACFDA
MLERDPRVFAIGEDVGFIGDVNQAFAGLQEKHGELRVTDTGIRECTIIGQGIGAALRGLR
PITEIQYLDYLLYAIQILSDDVACLQYRTKGGQKAPLIVRTRGHRLEGIWHSGSPIGMIL
NSIRGMHVLVPRDMTQAAGFYNTLLKADEPALVIECLNGYRLKERIPNNIGEFTVPLGKP
ETLREGTDITIVTYGSMCRIVLEAARQLEEFGISAEVIDVQTLLPFDVDHVITDSIRKTN
RVLFADEDVPGGASAYMMQQVVDEQGAWRWLDSKPQCLSAQPHRPAYSSDGDYFSKPNPE
DVFETVYEIMHEADPKAFPTIY