Protein Info for CA264_04245 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: NADH-quinone oxidoreductase subunit G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 909 PF13510: Fer2_4" amino acids 3 to 78 (76 residues), 51.5 bits, see alignment E=2.2e-17 TIGR01973: NADH dehydrogenase (quinone), G subunit" amino acids 4 to 649 (646 residues), 617.7 bits, see alignment E=1.4e-189 PF00111: Fer2" amino acids 6 to 67 (62 residues), 28.3 bits, see alignment 3.6e-10 PF10588: NADH-G_4Fe-4S_3" amino acids 88 to 124 (37 residues), 46.2 bits, see alignment (E = 6.7e-16) PF04879: Molybdop_Fe4S4" amino acids 224 to 275 (52 residues), 39.9 bits, see alignment 8.7e-14 PF00384: Molybdopterin" amino acids 278 to 398 (121 residues), 24 bits, see alignment E=4.7e-09 amino acids 481 to 650 (170 residues), 57.8 bits, see alignment E=2.4e-19

Best Hits

Swiss-Prot: 54% identical to NUOG_PSEAE: NADH-quinone oxidoreductase subunit G (nuoG) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00336, NADH dehydrogenase I subunit G [EC: 1.6.5.3] (inferred from 55% identity to pag:PLES_24631)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YPC9 at UniProt or InterPro

Protein Sequence (909 amino acids)

>CA264_04245 NADH-quinone oxidoreductase subunit G (Pontibacter actiniarum KMM 6156, DSM 19842)
MATIYIDNKPYEVTAGKNLLEACLSLGLDLPYFCYHPAMGSIGACRQCAVKMYRDDNDTT
GKLFMSCMEQVRDGMRVSIADLEAREFRAHVIGWLMTNHPHDCAVCDEGGACHLQDMTVM
TGHNYRAYRFDKRTYINQYLGPFLNHEMNRCIQCYRCVRYYKDYAGGKDLDVFAAHNHLY
FGRAEDGVLESEFSGNLAEVCPTGVFTDKTLKQHYTRKWDLTMAPSVCHHCSLGCNTIAG
ERYGTLRNITNRYNGEVNGYFLCDRGRFGYEFVNSAARIRKPLVRSQLPEATDKYTALKA
AASAIKTGRVIGIGSPRASVESNYVLKKLVGEGNFHHGASDTDYDLANLTLQLLQDGAAR
TLSLREVEKADAVFILGEDLTNTAPLLALAVRQSARQKPILEEVAKAKIPVWQDAAVREL
VQAEQGPLFIAHYTPTKLDELATRTYAAAPDAIARFGFAVAHLIHPDAPEVEGLSEAEEE
LAQQIAEALTEASKPLIVSGTSCGNERVLKAASNIATALVSRGKAAGISLVVPECNSMGL
AMLGGHKLESAFEAVLHGYADTVIILENDLYRRADASTVTDFLNSCRQIIVLDHLHSATT
EKADILLPAAPFSEADGTLVNNEGRAQRFFQVHPTAEEIQEGWHWLAELGTIIADEQISN
WQGYDDIIKAISEEVPALRGLHKTAPPSDFRIAGQRIPRAPHRFSGRTSMHAGNHVSEPK
PPEDPDSPLSYTMEGTRSQPPSAMIPFFWAPGWNSVQATNKYQQEVGGHLKGGDPGTRLL
EPTGAASYSTAVPQKFMPLEGHLYMLPLHHTFGSEEMSNHAPAITERIPDPYVAVNAADA
ARLKLSEGDLLGFTIEGTSYRLPIKTSHTIPSGTAGLPNGLPGVSFSALPAWAILNRNIQ
WKQQPQTIF