Protein Info for CA264_03875 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: HIT family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 133 PF11969: DcpS_C" amino acids 5 to 105 (101 residues), 44.3 bits, see alignment E=2.3e-15 PF01230: HIT" amino acids 12 to 101 (90 residues), 71.9 bits, see alignment E=5.9e-24

Best Hits

Swiss-Prot: 40% identical to YHI1_MYCTU: Uncharacterized HIT-like protein Rv0759c (Rv0759c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: K02503, Hit-like protein involved in cell-cycle regulation (inferred from 78% identity to sli:Slin_1055)

Predicted SEED Role

"HIT family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YP85 at UniProt or InterPro

Protein Sequence (133 amino acids)

>CA264_03875 HIT family protein (Pontibacter actiniarum KMM 6156, DSM 19842)
MEASIFTKIVNGEIPAYKIAEDDRYLAFLDVFPTAKGHTLVIPKQQVDYIFDLDDDLYLG
LMAFAKKVAPAIEKAIPCKRIGVAVVGIEVPHAHVHLIPLNSMQDMNFANKKKFSQEEFE
EVASKIREAYHAS