Protein Info for CA264_03640 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: TetR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 PF00440: TetR_N" amino acids 11 to 54 (44 residues), 57.6 bits, see alignment 8.6e-20 PF16295: TetR_C_10" amino acids 71 to 188 (118 residues), 37.6 bits, see alignment E=2.6e-13

Best Hits

KEGG orthology group: None (inferred from 40% identity to psn:Pedsa_3151)

Predicted SEED Role

"Transcription regulator of multidrug efflux pump operon, TetR (AcrR) family" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YP01 at UniProt or InterPro

Protein Sequence (190 amino acids)

>CA264_03640 TetR family transcriptional regulator (Pontibacter actiniarum KMM 6156, DSM 19842)
MEPIAEKKKAIFESTLELVTEHGFHGTPMSLVAKRAGVAAGTIYHYFESKEKLICELFEY
VRKQAVEVVLKEVQSDLPFKDCFFNLWFSLFSFYKENQNVLKFFEQFTNSPYNTEIAVLG
QDEFHRLLFRFFERGIQEGHLRDISPKILGVLAHSNIISTVKVQVTGRWEVQDGELEVIP
QILWDGMRDR