Protein Info for CA264_03100 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: Xaa-Pro aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 591 PF01321: Creatinase_N" amino acids 6 to 129 (124 residues), 54.4 bits, see alignment E=3.9e-18 amino acids 174 to 289 (116 residues), 22.5 bits, see alignment E=2.8e-08 PF16189: Creatinase_N_2" amino acids 149 to 306 (158 residues), 172.7 bits, see alignment E=1.3e-54 PF00557: Peptidase_M24" amino acids 309 to 520 (212 residues), 152.4 bits, see alignment E=3.1e-48 PF16188: Peptidase_M24_C" amino acids 531 to 591 (61 residues), 75.2 bits, see alignment E=6.4e-25

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 64% identity to phe:Phep_4014)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YNP6 at UniProt or InterPro

Protein Sequence (591 amino acids)

>CA264_03100 Xaa-Pro aminopeptidase (Pontibacter actiniarum KMM 6156, DSM 19842)
MTYKERLAAIRSQMKGEGVSAYIIPSADPHISEYVPDRYKCIEFASGFTGSAGTLVITED
AAHLWTDARYFVQGNEQLQGTGFELAKLRVQNAPEYIDWLAERLPEGATVAFDAKLISVS
LAQLLETQLTPIGLKINSDRDYLEPIWQDRPELPAAPAYLLGEDVVGETLESKLERLRKA
LKKHRADYHLISSLDDLAWLFNMRGSDVKCNPVVLGFALISQDKAMLFVDTTKLSEEDQE
KLRKAGVELETYDMIERAIAAIPADSILIDPRRNCYALYKQLPKEVRVVQDTNPTTFFKA
VKNEVEVEHTRKTMVKDGVALTRFFKWLEENIGKTKITELSVADKVREFRAEQEGFVGES
FDTIAGYKAHGALPHYKATPESDVELQPDGLFLLDSGGQYTSGTTDITRVVSLGNLTEEE
SIDYTLVLKGMIDGATARYPKGSKGYQIDAISRKPLWDYARNYGHGTGHGVGFFLNVHEG
PHVLNPTPTAVDLELGMISSVEPGLYRNGKHGIRIENLVLTVQDEQNEFGEFYTFEHLTM
ALIDTAPVKKELLEAHQIKWLNEYHQQVVENLGPHLQEDELAWLKEKAKAI