Protein Info for CA264_02365 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: exodeoxyribonuclease VII large subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 519 PF13742: tRNA_anti_2" amino acids 19 to 127 (109 residues), 65.4 bits, see alignment E=4.7e-22 TIGR00237: exodeoxyribonuclease VII, large subunit" amino acids 20 to 378 (359 residues), 293.8 bits, see alignment E=1.1e-91 PF02601: Exonuc_VII_L" amino acids 152 to 510 (359 residues), 255.7 bits, see alignment E=7.6e-80

Best Hits

Predicted SEED Role

"Exodeoxyribonuclease VII large subunit (EC 3.1.11.6)" in subsystem DNA repair, bacterial (EC 3.1.11.6)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.6

Use Curated BLAST to search for 3.1.11.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YNA8 at UniProt or InterPro

Protein Sequence (519 amino acids)

>CA264_02365 exodeoxyribonuclease VII large subunit (Pontibacter actiniarum KMM 6156, DSM 19842)
MSQIYIRQTVVYEEHQAPLSLYELHQQIREELEVAFPDSYWVVAEVAQVNVDRRKGHCYL
TLVDKGDDARQMLAQARATIWGSRYQMLGRYFEEKTGQPLKAGLKVLLQATVRFHELYGL
SLDITNIDPNYTIGDLARQRQETLKRLEAEGLLEANKELKLPLVPQRLAVISSGTAAGYQ
DFIHQLAGNSYGYYFETTLFPATVQGNEAPASVAQAFARISSNSDAFDAIVLIRGGGSQT
DLSCFDDYRIAAAIGHSPLPVLTGIGHERDESIADLVANTRLKTPTAVAGFLIDRFREAE
ESAEDMFDSIRMFAAQQLKLTSDKLERLSLRFNNITKQQLQNRKDKLESLSRGLLLKPKS
YLEAQRHLVSDMEKDISSGTKDLLHERQRYLQELSVCVEGKSQRYLHMKEHELNHLVHCL
ETEANDQLKKEQLLFSKYSDKLEYGAKGKLTNEHHRLRLLEMGIEANNPEKLLLRGYTLT
LLNGRIIKSTKDVKDGDVVETKMQDGTLHSMVVNVDTDE