Protein Info for CA264_01800 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: gluconate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 507 PF00370: FGGY_N" amino acids 6 to 248 (243 residues), 194.2 bits, see alignment E=3e-61 PF02782: FGGY_C" amino acids 258 to 453 (196 residues), 139.9 bits, see alignment E=9.5e-45

Best Hits

Swiss-Prot: 42% identical to GNTK_BACSU: Gluconokinase (gntK) from Bacillus subtilis (strain 168)

KEGG orthology group: K00851, gluconokinase [EC: 2.7.1.12] (inferred from 51% identity to cbk:CLL_A1310)

Predicted SEED Role

"Gluconokinase (EC 2.7.1.12)" in subsystem D-gluconate and ketogluconates metabolism or Entner-Doudoroff Pathway (EC 2.7.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YN12 at UniProt or InterPro

Protein Sequence (507 amino acids)

>CA264_01800 gluconate kinase (Pontibacter actiniarum KMM 6156, DSM 19842)
MQQSSIIGVDIGTTSTKSVAFGLTGEVLYYQTVEYPILSEEPGQAEQEPEQVLEAVLSTL
GKVLEWQQQRGCKLEGVSFSSAMHSLILMDAAGEPLTRCLIWADSRSHACADEIRNSPVG
HKIYLQTGTPVHPMSPLPKLCWLRQEQPELFGQAAKFIGIKEYVLYRLFGQYKVDQSVAS
AMGLFNIFEFEWHQDALEVAGVKPEQLPEPVPPTYTFRELKPAYASLLKIPADTPFVIGA
SDGCLANLASHAVRAGEAVVTIGTSGAVRVMSNKPATDLQERVFSYALNKDHFVLGGAVN
NGGVALRWFRDTFYAAETAEAMAKDQDIYELLNEVAESISAGADGLLFLPYLLGERAPIW
DGAARACFIGANYNHSRAHFLRAVMEGVIFGVNSVVQALEQTVGPISCIYANGGFSFSEL
WVQMLADVTGKKVQLTETPEGSAFGAALMGMYALQLLPSLEEAEHMIRVSRTYEPDMESH
RTYAKGYAVFEALYPKLKESFEQLNNA