Protein Info for CA264_01605 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: arginase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00491: Arginase
  • amino acids 5 to 305 (301 residues), 191.3 bits, E=1.3e-60
• TIGR01229: arginase
  • amino acids 6 to 308 (303 residues), 240.8 bits, E=1.1e-75

Best Hits

KEGG orthology group: K01476, arginase [EC: 3.5.3.1] (inferred from 51% identity to nve:NEMVE_v1g224716)

Predicted SEED Role

"Arginase (EC 3.5.3.1)" in subsystem Arginine and Ornithine Degradation (EC 3.5.3.1)

MetaCyc Pathways

• L-citrulline biosynthesis (7/8 steps found)
• L-arginine degradation VI (arginase 2 pathway) (4/4 steps found)
• L-arginine degradation I (arginase pathway) (3/3 steps found)
• superpathway of arginine and polyamine biosynthesis (13/17 steps found)
• urea cycle (4/5 steps found)
• superpathway of L-citrulline metabolism (9/12 steps found)
• superpathway of putrescine biosynthesis (3/4 steps found)
• L-N^δ-acetylornithine biosynthesis (5/7 steps found)
• L-arginine degradation VII (arginase 3 pathway) (1/2 steps found)
• L-canavanine degradation I (1/2 steps found)
• putrescine biosynthesis III (1/2 steps found)
• superpathway of polyamine biosynthesis I (5/8 steps found)
• superpathway of polyamine biosynthesis II (4/8 steps found)
• superpathway of hyoscyamine (atropine) and scopolamine biosynthesis (4/16 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.1

Sequence Analysis Tools

See A0A1X9YMW9 at UniProt or InterPro

Protein Sequence (323 amino acids)

>CA264_01605 arginase (Pontibacter actiniarum KMM 6156, DSM 19842)
MKKVKLIEVRSELGAGTRGASMGIEALRVACWDKGSDYFKRFNSVSVPDLNYTLFDPDVF
PNAHRIDSILTVQKNIARAVEQTIAMDMFPLVLAGDHSNAHGTIAGIKAAYPDKTLGVIW
IDAHADIHSPYTSPSGNVHGMPLAMALNVDNLDRQINDPAPETVFFWNSLKKLGYDGPKL
KPEHLVYIVVRDTEEPEDYFIKKYGIKNFTYDEVNKKGIPQVAQEALERVKDCDIIYVSF
DVDSLDSKFSKGTGTPVETGLTVTQAKELNYLLLQDPRVVCYEMTEINPTLDTENTMAEN
AFDILEAATEAILQKESKSTATH