Protein Info for CA264_01325 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: protoheme IX farnesyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 transmembrane" amino acids 28 to 47 (20 residues), see Phobius details amino acids 53 to 76 (24 residues), see Phobius details amino acids 97 to 117 (21 residues), see Phobius details amino acids 123 to 141 (19 residues), see Phobius details amino acids 149 to 171 (23 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 219 to 240 (22 residues), see Phobius details amino acids 247 to 268 (22 residues), see Phobius details amino acids 275 to 296 (22 residues), see Phobius details TIGR01473: protoheme IX farnesyltransferase" amino acids 22 to 298 (277 residues), 274.9 bits, see alignment E=5.2e-86 PF01040: UbiA" amino acids 37 to 283 (247 residues), 198.3 bits, see alignment E=6.8e-63

Best Hits

Swiss-Prot: 57% identical to COXX_CYTH3: Protoheme IX farnesyltransferase (ctaB) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)

KEGG orthology group: K02301, protoheme IX farnesyltransferase [EC: 2.5.1.-] (inferred from 66% identity to mtt:Ftrac_3695)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.-

Use Curated BLAST to search for 2.5.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YMV0 at UniProt or InterPro

Protein Sequence (299 amino acids)

>CA264_01325 protoheme IX farnesyltransferase (Pontibacter actiniarum KMM 6156, DSM 19842)
MYTQQKSDTLLHASTMATKASAYFQLLKFRLSLTVAFSSAIGFILGYPNTHWYDILLVML
GGMLVTGSANIINQILEKDLDKLMKRTSKRPLPTGQLSVTEAAVFCVMLGLAGLALLGFY
FNALTAALSLLSLVLYGFVYTPLKRMNPICVFVGAIPGGMPPLIGWVAATGAIEIEAIIL
FGIQFFWQFPHFWAIAWVLDDDYKKAGFKMLPMAGGKNLKTAIQIMIYTLVLIPLSLLPL
QFGMTGATSAMVAVVCGVLFLAQTFYLMRTCSKKAAMSIMFGSFLYLPIVQIAFVLDKI