Protein Info for CA264_00955 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: valine--tRNA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 877 TIGR00422: valine--tRNA ligase" amino acids 4 to 859 (856 residues), 956.5 bits, see alignment E=6.5e-292 PF00133: tRNA-synt_1" amino acids 15 to 575 (561 residues), 423.6 bits, see alignment E=2e-130 PF09334: tRNA-synt_1g" amino acids 42 to 189 (148 residues), 32.4 bits, see alignment E=1.2e-11 PF13603: tRNA-synt_1_2" amino acids 246 to 311 (66 residues), 37.7 bits, see alignment 3.9e-13 PF08264: Anticodon_1" amino acids 616 to 759 (144 residues), 121.1 bits, see alignment E=9.1e-39 PF10458: Val_tRNA-synt_C" amino acids 813 to 877 (65 residues), 54.5 bits, see alignment 2.9e-18

Best Hits

Swiss-Prot: 61% identical to SYV_PARD8: Valine--tRNA ligase (valS) from Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)

KEGG orthology group: K01873, valyl-tRNA synthetase [EC: 6.1.1.9] (inferred from 64% identity to mtt:Ftrac_0821)

Predicted SEED Role

"Valyl-tRNA synthetase (EC 6.1.1.9)" (EC 6.1.1.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YMN5 at UniProt or InterPro

Protein Sequence (877 amino acids)

>CA264_00955 valine--tRNA ligase (Pontibacter actiniarum KMM 6156, DSM 19842)
MSISTKYNPKEVEKKWYDSWMQRGFFRSKPNPNKEPYTIVIPPPNVTGVLHMGHMLNNTI
QDVLIRRARMQGKEACWVPGTDHASIATEAKVVAMLKERGISKSDISREEFLTYAWEWKE
KYGGIILDQLKKLGASCDWDRTRFTMEDDMSAAVIEVFVDLYRKGQIYRGVRMVNWDPQG
KTALSDEEVVPKDTMAKMYHLNYEVVAEGAAAPTYITVATSRPETIMADVAVAVNPNDER
YTHLHGKSVRIPLLGKEVPVILDEYVSIDFGTGALKVTPAHDLNDYELGQKHKLPTIDIL
NNDGTLNEQAQLYVGQDRFAARRNIVKDLQEAGHLVKIEEYASVLQTSERTGAVIEPRLS
MQWWCKMDKMAGPALESVMNDEIRLHPPKFKNMYRSWMENIRDWCISRQLWWGQRIPAYY
LPDGSFVVAATEEEALVLARKESGNEALQLSDLRQDEDVLDTWFSSWLWPISVFDGFKDP
DNKDILYYYPTNDLVTAPEILFFWVARMIMAGYEFRNELPFKNVYLTGIVRDAQGRKMSK
SLGNSPDPLDLIDQYGADGVRAGMLFSSPAGNDLLFDEKLVEQGRNFSNKIWNAFRLIKG
WEVDESLPFPNETAVKWFESRFNEAFVQIEDHFSKFRISDALLTVYKLVWDDFCSNYLEM
IKPAYQQPIDKQTIEATTAFLEKVLKVLHPFMPFITEEIWHDLRERKDKEYLIVSAWPKK
DKFDKQIIEQMESVLNVIGAIRNIRNSKNIPNSKQLDLFIKAISHDQYEPFLGIIRKLAN
LNEVQYVEENLEGAISFIVAGDEFFIPMEGNIDVAAERERLTKELEYTKGFLLAVDKKLS
NERFVSGAPEAVIANERKKKADAEAKINAIEQSLAAL