Protein Info for CA264_00825 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 PF01596: Methyltransf_3" amino acids 9 to 92 (84 residues), 25.7 bits, see alignment E=1.3e-09 PF06325: PrmA" amino acids 27 to 113 (87 residues), 28 bits, see alignment E=3e-10 PF05175: MTS" amino acids 38 to 158 (121 residues), 47.7 bits, see alignment E=2.8e-16 PF13649: Methyltransf_25" amino acids 41 to 132 (92 residues), 30.3 bits, see alignment E=1.1e-10

Best Hits

Swiss-Prot: 48% identical to TRMN6_CYTH3: tRNA1(Val) (adenine(37)-N6)-methyltransferase (CHU_2705) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)

KEGG orthology group: None (inferred from 48% identity to chu:CHU_2705)

Predicted SEED Role

"tRNA (adenine37-N(6))-methyltransferase TrmN6 (EC 2.1.1.223)" (EC 2.1.1.223)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.223

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YML5 at UniProt or InterPro

Protein Sequence (238 amino acids)

>CA264_00825 methyltransferase (Pontibacter actiniarum KMM 6156, DSM 19842)
MRNSYFQFKQFRVEQDKCAMKVCTDSCVFGAYVAVAGAQRILDIGTGTGLLSLMVAQRSH
ASIDAVEINKEAQQQAHENFAISPWAKRLQLHPMSLQEFAKQAPPAYDVLLSNPPFFLSS
LKSPDAARNTARHTGELLFEDILAFAQQHLTAQGKLYLLLPPAEAAVFASLAKASDLYLA
EVLQVFTYHGGKCIRHIQTYTFGHRGAPDVKDFYIREEDKTTYTAQFAELLREYYLAF