Protein Info for CA264_00400 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: alkyl hydroperoxide reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 PF00578: AhpC-TSA" amino acids 5 to 152 (148 residues), 116.9 bits, see alignment E=8.7e-38 PF08534: Redoxin" amino acids 5 to 161 (157 residues), 52.4 bits, see alignment E=7.8e-18 PF10417: 1-cysPrx_C" amino acids 173 to 207 (35 residues), 39.1 bits, see alignment 7.8e-14

Best Hits

Swiss-Prot: 49% identical to PRDX2_MOUSE: Peroxiredoxin-2 (Prdx2) from Mus musculus

KEGG orthology group: K03386, peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC: 1.11.1.15] (inferred from 72% identity to mtt:Ftrac_1506)

Predicted SEED Role

"Alkyl hydroperoxide reductase subunit C-like protein" in subsystem Oxidative stress or Rubrerythrin or Thioredoxin-disulfide reductase

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.15

Use Curated BLAST to search for 1.11.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YMC4 at UniProt or InterPro

Protein Sequence (212 amino acids)

>CA264_00400 alkyl hydroperoxide reductase (Pontibacter actiniarum KMM 6156, DSM 19842)
MAVLVGKKAPSFKTMAVENGEFVEDFSLEQYLGKKHVIFYFYPMDFTFVCPTEIIAFQDR
MEEFERKGVAVVGCSTDTHFSHFAWLNTPREQGGIEGVNYPLVADAAKTIAQNYDVLAGH
YEYNEEGEVTFVGDPVAYRGLFLIDKEGIVRHQVVNDMPLGRSIDEALRMVDALQYFEEK
GEVCPANWEEGKEGMQATKEGVSSYLSANAAH