Protein Info for CA264_00025 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: RIP metalloprotease RseP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 57 to 72 (16 residues), see Phobius details amino acids 99 to 122 (24 residues), see Phobius details amino acids 364 to 385 (22 residues), see Phobius details amino acids 415 to 433 (19 residues), see Phobius details TIGR00054: RIP metalloprotease RseP" amino acids 1 to 435 (435 residues), 265.9 bits, see alignment E=3.1e-83 PF02163: Peptidase_M50" amino acids 10 to 422 (413 residues), 210 bits, see alignment E=7.2e-66 PF00595: PDZ" amino acids 218 to 274 (57 residues), 34.2 bits, see alignment 6.8e-12 PF13180: PDZ_2" amino acids 222 to 284 (63 residues), 31.6 bits, see alignment E=4.3e-11 PF17820: PDZ_6" amino acids 223 to 275 (53 residues), 59.3 bits, see alignment 6.8e-20

Best Hits

KEGG orthology group: K11749, regulator of sigma E protease [EC: 3.4.24.-] (inferred from 61% identity to dfe:Dfer_4131)

Predicted SEED Role

"Membrane-associated zinc metalloprotease" in subsystem Sex pheromones in Enterococcus faecalis and other Firmicutes

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YM53 at UniProt or InterPro

Protein Sequence (437 amino acids)

>CA264_00025 RIP metalloprotease RseP (Pontibacter actiniarum KMM 6156, DSM 19842)
MDILIMVGQLILGLTILVGLHELGHMLAAKWFGMRVEKYAIGFPPKVFGKKIGETEYMLG
LIPLGGFVKISGMVDESMDTEALKEEPKPWEFRAKPAWQRLIVMMGGIIVNVITGIVIYI
ALTYNYGESYLPASEAKYGVIANDIGEDIGFQTGDKIVAVNGQKLEKFDDVYSMDALLGR
DSYYTIDRNGQLIDLKVPVDLMDRLADREDRMLFVQPRQPFKVGQVAKGSAADKAGLQEG
DFITMINGKSVMFFHELQEALHANKAKPVTMTIERGGKPIKLQAQVSEEGTIGFMPVILL
ESATRQFSLGESIPLGTEQAFGVITANLKGFGKIFRGEVSASKSLSGPIGIAQIFGDTFN
WYKFWSITAMLSMVLAFMNFLPIPALDGGHVVFLTYEMISGRKPSDNFLENAQKVGMVLL
LGLMAFAIFNDVFKIIF