Protein Info for BNILDI_23050 in Escherichia coli ECRC62

Name: bcsA
Annotation: Glycosyl transferase family 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00535: Glycos_transf_2
  • amino acids 34 to 200 (167 residues), 97.3 bits, E=2e-31
• PF13641: Glyco_tranf_2_3
  • amino acids 34 to 253 (220 residues), 61.8 bits, E=1.9e-20
• PF13506: Glyco_transf_21
  • amino acids 100 to 252 (153 residues), 34.6 bits, E=2.8e-12
• PF13632: Glyco_trans_2_3
  • amino acids 115 to 310 (196 residues), 45.2 bits, E=2.1e-15

Best Hits

Swiss-Prot: 99% identical to YAIP_ECOLI: Uncharacterized glycosyltransferase YaiP (yaiP) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b0363)

Predicted SEED Role

"Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24)" in subsystem Rhamnose containing glycans or dTDP-rhamnose synthesis or linker unit-arabinogalactan synthesis (EC 2.7.7.24)

MetaCyc Pathways

• superpathway of enterobacterial common antigen biosynthesis (9/10 steps found)
• dTDP-N-acetylthomosamine biosynthesis (4/4 steps found)
• O-antigen building blocks biosynthesis (E. coli) (8/11 steps found)
• dTDP-β-L-rhamnose biosynthesis (3/5 steps found)
• dTDP-β-D-fucofuranose biosynthesis (2/4 steps found)
• dTDP-6-deoxy-α-D-allose biosynthesis (2/4 steps found)
• dTDP-N-acetylviosamine biosynthesis (2/4 steps found)
• dTDP-α-D-mycaminose biosynthesis (2/5 steps found)
• dTDP-3-acetamido-α-D-fucose biosynthesis (2/5 steps found)
• dTDP-3-acetamido-3,6-dideoxy-α-D-glucose biosynthesis (2/5 steps found)
• dTDP-4-O-demethyl-β-L-noviose biosynthesis (2/5 steps found)
• dTDP-β-L-digitoxose biosynthesis (3/7 steps found)
• dTDP-β-L-olivose biosynthesis (3/7 steps found)
• dTDP-α-D-ravidosamine and dTDP-4-acetyl-α-D-ravidosamine biosynthesis (2/6 steps found)
• dTDP-D-desosamine biosynthesis (2/6 steps found)
• dTDP-L-daunosamine biosynthesis (2/6 steps found)
• dTDP-sibirosamine biosynthesis (2/6 steps found)
• dTDP-β-L-4-epi-vancosamine biosynthesis (3/8 steps found)
• dTDP-β-L-megosamine biosynthesis (3/8 steps found)
• dTDP-β-L-mycarose biosynthesis (2/7 steps found)
• dTDP-α-D-forosamine biosynthesis (3/9 steps found)
• dTDP-α-D-olivose, dTDP-α-D-oliose and dTDP-α-D-mycarose biosynthesis (3/9 steps found)
• superpathway of dTDP-glucose-derived O-antigen building blocks biosynthesis (5/19 steps found)
• superpathway of novobiocin biosynthesis (3/19 steps found)
• superpathway of erythromycin biosynthesis (2/19 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (11/33 steps found)
• superpathway of megalomicin A biosynthesis (3/22 steps found)
• superpathway of dTDP-glucose-derived antibiotic building blocks biosynthesis (3/23 steps found)

KEGG Metabolic Maps

• Polyketide sugar unit biosynthesis
• Streptomycin biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.24

Use Curated BLAST to search for 2.7.7.24

Protein Sequence (398 amino acids)

>BNILDI_23050 Glycosyl transferase family 2 (Escherichia coli ECRC62)
MKTWIFICMSIAMLLWFLSTLRRKPSQKKGCIDAIIPAYNEGPCLAQSLDNLLRNPYFCR
VICVNDGSTDNTEAVMAEVKRKWGDRFVAITQKNTGKGGALMNGLNYATCDQVFLSDADT
YVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHIRATVKLPMIVMKRTLQQLLG
GAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTLVANGYRIRQANRCIVYPQECNS
PREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIFPMLLVVIYGVGIYLTTWFNEFITT
GPHGVVLAMFPLIWIGVVCVIGAFSAWFHRCWLLVPLAPLSVVYVLLAYAIWIIYGLIAF
FTGREPQRDKPTRYSALVEASTAYSQPSVTGTEKLSEA