Protein Info for BNILDI_17135 in Escherichia coli ECRC62

Name: dcp
Annotation: peptidyl-dipeptidase Dcp

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 678 transmembrane" amino acids 597 to 612 (16 residues), see Phobius details PF01432: Peptidase_M3" amino acids 227 to 675 (449 residues), 507.6 bits, see alignment E=2.5e-156

Best Hits

Swiss-Prot: 99% identical to DCP_ECOLI: Dipeptidyl carboxypeptidase (dcp) from Escherichia coli (strain K12)

KEGG orthology group: K01284, peptidyl-dipeptidase Dcp [EC: 3.4.15.5] (inferred from 99% identity to eco:b1538)

MetaCyc: 99% identical to peptidyl-dipeptidase Dcp (Escherichia coli K-12 substr. MG1655)
Peptidyl-dipeptidase Dcp. [EC: 3.4.15.5]

Predicted SEED Role

"Dipeptidyl carboxypeptidase Dcp (EC 3.4.15.5)" in subsystem Protein degradation (EC 3.4.15.5)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.15.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (678 amino acids)

>BNILDI_17135 peptidyl-dipeptidase Dcp (Escherichia coli ECRC62)
MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIAAIALNPQTPDFNNTIL
ALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELANDIYLNGELFARVDAVWQRR
ESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKVLNTEAATLTSQFNQRLLAANKSG
GLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATREKLF
IAGWTRAEKNDGNDTRAIIQRLVEIRAQQAKLLGFPHYAAWKIADQMAKTPEAALNFMRE
IVPAARQRASDELASIQAVIDKQQGGFSAQPWDWAFYAEQVRREKFDLDEAQLKPYFELN
TVLNEGVFWTANQLFGIKFVERFDIPVYHPDVRVWEIFDHNGVGLALFYGDFFARDSKSG
GAWMGNFVEQSTLNETHPVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQ
RYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFN
KGYEMSELLSAALLDMRWHCLEENEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHI
FGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENGQRFREAILSRGNSEDLERLYRQW
RGKAPQIMPMLQHRGLNI