Protein Info for BNILDI_10780 in Escherichia coli ECRC62

Name: cas5e
Annotation: type I-E CRISPR-associated protein Cas5/CasD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 TIGR01868: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI" amino acids 3 to 233 (231 residues), 159.7 bits, see alignment E=9.5e-51 PF09704: Cas_Cas5d" amino acids 4 to 232 (229 residues), 118 bits, see alignment E=2.9e-38 TIGR02593: CRISPR-associated protein Cas5" amino acids 4 to 46 (43 residues), 43.9 bits, see alignment 1.5e-15

Best Hits

KEGG orthology group: None (inferred from 99% identity to eoi:ECO111_3481)

Predicted SEED Role

"CRISPR-associated protein, Cas5e family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (248 amino acids)

>BNILDI_10780 type I-E CRISPR-associated protein Cas5/CasD (Escherichia coli ECRC62)
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRH
YSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWM
VAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQY
QDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSK
EEPCTSQE