Protein Info for BNILDI_07525 in Escherichia coli ECRC62

Name: uhpC
Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 48 to 68 (21 residues), see Phobius details amino acids 77 to 103 (27 residues), see Phobius details amino acids 160 to 182 (23 residues), see Phobius details amino acids 230 to 251 (22 residues), see Phobius details amino acids 263 to 284 (22 residues), see Phobius details amino acids 300 to 317 (18 residues), see Phobius details amino acids 323 to 346 (24 residues), see Phobius details amino acids 357 to 381 (25 residues), see Phobius details amino acids 387 to 408 (22 residues), see Phobius details PF01306: LacY_symp" amino acids 13 to 101 (89 residues), 26.9 bits, see alignment E=4.3e-10 PF07690: MFS_1" amino acids 15 to 374 (360 residues), 190.3 bits, see alignment E=9.4e-60 PF11700: ATG22" amino acids 365 to 413 (49 residues), 24.4 bits, see alignment 2.3e-09

Best Hits

KEGG orthology group: None (inferred from 73% identity to cro:ROD_03791)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (414 amino acids)

>BNILDI_07525 MFS transporter (Escherichia coli ECRC62)
MLQIKARTKILALFCAMSFLMYVDRVNLSATAGLIKDELGLSNTELGVIFSAFAYTYAVF
QIIGGWFVDRLGSRRMIIFCGIIWVIATMATGFVGGFISLFLARLLLGVGEGAALPSQAR
AITYWFKPQQRGFVQGVTHSFSRLGNAITPPIIVALVAFWSWRGAFISLAIVTFIWLISW
IISYKDDPRDHSGMTEEELEGVPIFEKKDLKVKAEPTPWRALIKRMGPTMGVYFCYGWTS
WLFFTWLPTFFMHGRGMDLKSSALFTAGVFLSGVVGNTVGGVISDKVLKMTGNLVAARRN
VILFSFISVLFLLVPVINTDSLLIMTICLSVAFFCLELTIGPIWAVPMDITPKYVGIASG
LMNAGSAVAGIISPIVFGIIIDKTGNWSLPFYGSVALLIIGIFLTFFMRPDKSL