Protein Info for BNILDI_03565 in Escherichia coli ECRC62

Name: yiaC
Annotation: N-acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 146 transmembrane" amino acids 59 to 77 (19 residues), see Phobius details PF00583: Acetyltransf_1" amino acids 12 to 120 (109 residues), 60.2 bits, see alignment E=4.7e-20 PF13673: Acetyltransf_10" amino acids 47 to 123 (77 residues), 50.8 bits, see alignment E=3.4e-17 PF13508: Acetyltransf_7" amino acids 48 to 121 (74 residues), 51.3 bits, see alignment E=2.6e-17

Best Hits

Swiss-Prot: 98% identical to YIAC_ECOLI: Peptidyl-lysine N-acetyltransferase YiaC (yiaC) from Escherichia coli (strain K12)

KEGG orthology group: K03826, putative acetyltransferase [EC: 2.3.1.-] (inferred from 98% identity to eco:b3550)

MetaCyc: 98% identical to peptidyl-lysine N-acetyltransferase YiaC (Escherichia coli K-12 substr. MG1655)
2.3.1.-

Predicted SEED Role

"PhnO protein" in subsystem Alkylphosphonate utilization

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (146 amino acids)

>BNILDI_03565 N-acetyltransferase (Escherichia coli ECRC62)
MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAYLANAQNWVWEEDGKLL
GFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRYPHLMLEVYQKNQPAIDFYRAQGF
HIVDCAWQDETQLPTWIMSWPVVQTL