Protein Info for BNILDI_01415 in Escherichia coli ECRC62
Name: kbaZ
Annotation: tagatose-bisphosphate aldolase subunit KbaZ
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to KBAZ_ECO24: D-tagatose-1,6-bisphosphate aldolase subunit KbaZ (kbaZ) from Escherichia coli O139:H28 (strain E24377A / ETEC)
KEGG orthology group: K00917, tagatose 6-phosphate kinase [EC: 2.7.1.144] (inferred from 100% identity to eco:b3132)MetaCyc: 100% identical to putative tagatose-1,6-bisphosphate aldolase 1 chaperone (Escherichia coli K-12 substr. MG1655)
Predicted SEED Role
"Tagatose-6-phosphate kinase AgaZ (EC 2.7.1.144)" in subsystem N-Acetyl-Galactosamine and Galactosamine Utilization (EC 2.7.1.144)
MetaCyc Pathways
- superpathway of hexitol degradation (bacteria) (18/18 steps found)
- galactitol degradation (5/5 steps found)
- D-galactosamine and N-acetyl-D-galactosamine degradation (4/4 steps found)
- N-acetyl-D-galactosamine degradation (4/5 steps found)
- lactose degradation I (2/5 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.144
Use Curated BLAST to search for 2.7.1.144
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (426 amino acids)
>BNILDI_01415 tagatose-bisphosphate aldolase subunit KbaZ (Escherichia coli ECRC62) VKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYT GMTPADFRGFVCQLAESLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAG FKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCLEHFGEADLEYVIGTEVPVPG GAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQ PAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSL AAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPD SQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYH TACEGQ