Protein Info for BACOVA_05376 in Bacteroides ovatus ATCC 8483
Annotation: putative amidophosphoribosyltransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00764, amidophosphoribosyltransferase [EC: 2.4.2.14] (inferred from 95% identity to bth:BT_4582)Predicted SEED Role
"Amidophosphoribosyltransferase (EC 2.4.2.14)" in subsystem De Novo Purine Biosynthesis (EC 2.4.2.14)
MetaCyc Pathways
- superpathway of histidine, purine, and pyrimidine biosynthesis (42/46 steps found)
- superpathway of purine nucleotides de novo biosynthesis I (21/21 steps found)
- superpathway of purine nucleotides de novo biosynthesis II (23/26 steps found)
- superpathway of 5-aminoimidazole ribonucleotide biosynthesis (6/6 steps found)
- 5-aminoimidazole ribonucleotide biosynthesis I (5/5 steps found)
- 5-aminoimidazole ribonucleotide biosynthesis II (5/5 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.4.2.14
Use Curated BLAST to search for 2.4.2.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (469 amino acids)
>BACOVA_05376 putative amidophosphoribosyltransferase (Bacteroides ovatus ATCC 8483) MGGFFGTVSKTSCVTDLFYGTDYNSHLGTKRGGLATYSEEKGFIRSIHNLESTYFRTKFE GELDKFKGNAGIGIISDTDAQPIIINSHLGRFAIVTVAKIVNIQELEEELLSQNMHFAEL SSSNTNQTELIALLIIQGRTFVEGIENVFKHIKGSCSMLLLTEDGSIIAARDRWGRTPVV IGRKDGAYAATSESSSFPNLDYEIERYLGPGEIVRMYDDHVDQLRKPNEDMQICSFLWVY YGFPTSCYEGKNVEEVRFTSGLKMGQTDESEVDCACGIPDSGVGMALGYAEGKGVPYHRA ISKYTPTWPRSFTPSNQEMRSLVAKMKLIPNRAMLQNKRLLFCDDSIVRGTQLRDNVKIL YDYGAKEVHMRIACPPLIYACPFVGFSASKNALELITRRIIKELEGDENKNLEKYATTGS PEYDKMVSIIAERFGLSSLKFNTLETLIEAIGLPKCKVCTHCFDGSSHF