Protein Info for BACOVA_05281 in Bacteroides ovatus ATCC 8483

Annotation: xanthine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 52 to 70 (19 residues), see Phobius details amino acids 89 to 114 (26 residues), see Phobius details amino acids 131 to 155 (25 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 239 to 260 (22 residues), see Phobius details amino acids 326 to 348 (23 residues), see Phobius details amino acids 354 to 373 (20 residues), see Phobius details amino acids 385 to 404 (20 residues), see Phobius details amino acids 410 to 433 (24 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 12 to 432 (421 residues), 385.6 bits, see alignment E=3e-119 PF00860: Xan_ur_permease" amino acids 18 to 401 (384 residues), 311.9 bits, see alignment E=2.8e-97 TIGR03173: xanthine permease" amino acids 22 to 433 (412 residues), 457.8 bits, see alignment E=2.9e-141

Best Hits

Swiss-Prot: 51% identical to XANP_ECO57: Xanthine permease XanP (xanP) from Escherichia coli O157:H7

KEGG orthology group: K03458, nucleobase:cation symporter-2, NCS2 family (inferred from 94% identity to bth:BT_4473)

MetaCyc: 51% identical to xanthine:H+ symporter XanP (Escherichia coli K-12 substr. MG1655)
RXN-5076

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>BACOVA_05281 xanthine permease (Bacteroides ovatus ATCC 8483)
MKTDLIYGVEDRPPFKDALFAALQHLLAIFVAIITPPLIIASALKLDVEKTSFLVSMSLF
ASGVSTFIQCRRFGAIGAKLLCIQGTSFSFIGPIIATGLVGGLPLIFGSCMAAAPIEMIV
SRTFKYLRNIITPLVSGIVVLLIGLSLIKVGIVSCGGGYAAMDNGTFATWENLSIAGLVL
LSVLFFNRCRNKYLRMSSIVLGLCLGYALAFALGKVDMSSLNVEMLMSFNIPQPFKYGVD
FNVSSFIAIGLVYLITAIEATGDVTANSMISGLPIEGDSYLKRVSGGVMADGFNSFLAGV
FNSFPNSIFAQNNGIIQLTGVASRYVGYYIAAMLVLLGLFPIVGAVFSLMPDPVLGGATL
LMFGTVAAAGIRIVSSQEIGRKETLVLAVSLSLGLGVELMPDVLQQTPEAIRSIFSSGIT
TGGLTAIIANIVIRVKE