Protein Info for BACOVA_05239 in Bacteroides ovatus ATCC 8483

Annotation: heterodisulfide reductase, C subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 PF13183: Fer4_8" amino acids 19 to 83 (65 residues), 38.8 bits, see alignment E=1.7e-13 PF13534: Fer4_17" amino acids 22 to 84 (63 residues), 28.6 bits, see alignment E=2.4e-10 PF12838: Fer4_7" amino acids 22 to 82 (61 residues), 30 bits, see alignment E=8.7e-11

Best Hits

KEGG orthology group: K03390, heterodisulfide reductase subunit C [EC: 1.8.98.1] (inferred from 49% identity to aps:CFPG_238)

Predicted SEED Role

"CoB--CoM heterodisulfide reductase subunit C (EC 1.8.98.1)" in subsystem Anaerobic respiratory reductases or H2:CoM-S-S-HTP oxidoreductase or Methanogenesis (EC 1.8.98.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.8.98.1

Use Curated BLAST to search for 1.8.98.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (184 amino acids)

>BACOVA_05239 heterodisulfide reductase, C subunit (Bacteroides ovatus ATCC 8483)
MENKECISYDLEQKTGIDVSYCYQCGKCTAGCVLSEEMDYAPSYILRLLQTKNAQNDRRV
LSSNAIWICLNCENCIARCPKEINIPEVMDYLREKSRKEGCISKESRPVVAFHSAFLESV
KRTGRLYEVGLVAGFKARTLRLTQDLNVAPVMFVKGKLNLLPERVKDENKIKKIFAQTIE
KTQK